CDK5 Protein (GST tag)
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- 抗原 See all CDK5 蛋白
- CDK5 (Cyclin-Dependent Kinase 5 (CDK5))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This CDK5 protein is labelled with GST tag.
- 原理
- Recombinant Human CDK5 Protein (GST Tag)
- 序列
- Met 1-Pro 292
- 产品特性
- A DNA sequence encoding the human CDK5 isoform 1 (NP_004926.1) (Met 1-Pro 292) was fused with the GST tag at the N-terminus.
- 纯度
- > 94 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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- Discover our top product CDK5 蛋白
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Cyclin-Dependent Kinase 5 (CDK5) (AA 1-292) protein (GST tag)
CDK5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cyclin-Dependent Kinase 5 (CDK5) (AA 1-292) (Active) protein (GST tag)CDK5 宿主: 人 宿主: Insect Cells Recombinant SDS, Func Active
Cyclin-Dependent Kinase 5 (CDK5) (AA 195-292) protein (GST tag)CDK5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cyclin-Dependent Kinase 5 (CDK5) (AA 1-292) protein (Strep Tag)Crystallography grade CDK5 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Cyclin-Dependent Kinase 5 (CDK5) (AA 1-292) protein (Strep Tag)Crystallography grade CDK5 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Cyclin-Dependent Kinase 5 (CDK5) (AA 1-292), (full length) protein (His-SUMO Tag)CDK5 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, 0.5 mM GSH, pH 7.0
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CDK5 (Cyclin-Dependent Kinase 5 (CDK5))
- 别名
- CDK5 (CDK5 产品)
- 别名
- PSSALRE Protein, AW048668 Protein, Crk6 Protein, CDK5 Protein, CG8203 Protein, DmCdk5 Protein, Dmel\\CG8203 Protein, cdk5 Protein, zgc:101604 Protein, cyclin dependent kinase 5 Protein, cyclin-dependent kinase 5 Protein, Cyclin-dependent kinase 5 Protein, cyclin-dependent kinase 5 L homeolog Protein, Cyclin-dependent-like kinase 5 Protein, CDK5 Protein, Cdk5 Protein, cdk5 Protein, cdk5.L Protein, cdk-5 Protein
- 背景
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Background: Cell division protein kinase 5, also known as Cyclin-dependent kinase 5, Serine/threonine-protein kinase PSSALRE, Tau protein kinase II catalytic subunit, TPKII catalytic subunit and CDK5, is a cytoplasm protein which belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family and CDC2 / CDKX subfamily. Cyclin-dependent kinases (Cdks) are a family of proline-directed Ser/Thr kinases known for their role in the control of cell cycle progression. In 1992, this family was joined by CDK5, which is an atypical member in that it uses its own activators and is multifunctional, playing important regulatory roles in multiple cellular functions. CDK5, unlike other Cdks, is not regulated by cyclins, and its activity is primarily detected in postmitotic neurons in developing and adult nervous systems. CDK5 is activated by association with a neuron-specific activator, p35 or its isoform p39. CDK5 is probably involved in the control of the cell cycle. It interacts with D1 and D3-type G1 cyclins. CDK5 can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. It also interacts with p35 which activates the kinase. CDK5 plays important roles in various neuronal activities, including neuronal migration, synaptic activity, and neuronal cell death.
Synonym: PSSALRE
- 分子量
- 59.6 kDa
- NCBI登录号
- NP_004926
- 途径
- Cell Division Cycle, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
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