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CNTN3 Protein (Fc Tag)

CNTN3 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
产品编号 ABIN7321137
发货至: 中国
  • 抗原 See all CNTN3 products
    CNTN3 (Contactin 3 (Plasmacytoma Associated) (CNTN3))
    蛋白类型
    Recombinant
    宿主
    • 4
    • 4
    • 1
    大鼠
    资源
    • 4
    • 3
    • 2
    HEK-293 Cells
    标记
    This CNTN3 protein is labelled with Fc Tag.
    原理
    Recombinant Rat Contactin 3/CNTN3 Protein (Fc Tag)
    序列
    Met1-Gly1001
    产品特性
    A DNA sequence encoding the rat CNTN3 (Met1-Gly1001) was expressed with the Fc region of human IgG1 at the C-terminus.
    纯度
    > 85 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CNTN3 (Contactin 3 (Plasmacytoma Associated) (CNTN3))
    别名
    Contactin 3/CNTN3 (CNTN3 产品)
    别名
    Pang Protein, BIG-1 Protein, PANG Protein, PCS Protein, contactin 3 Protein, CNTN3 Protein, Cntn3 Protein
    背景

    Background: Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that are expressed exclusively in the nervous system. The subgroup consists of six members: Contactin-1, Contactin-2(TAG-1), Contactin-3(BIG-1), BIG-2, Contactin-5(NB-2) and NB-3. Since their identification in the late 1980s, Contactin-1 and Contactin-2 have been studied extensively. Axonal expression and the neurite extension activity of Contactin-1 and Contactin-2 attracted researchers to study the function of these molecules in axon guidance during development. Contactin-1 and Contactin-2 have come to be known as the principal molecules in the function and maintenance of myelinated neurons. In contrast, the function of the other four members of this subgroup remained unknown until recently. Contactin-3, also known as CNTN3 ( BIG-1 in rat and PANG in mouse ), is a GPI-linked glycoprotein that is expressed on cerebellar Purkinje cells, amygdaloid and thalamic neurons and olfactory granule cells. In the brain, Contactin-3 is expressed in frontal lobe, occipital lobe, cerebellum and amygdala. Contactin-3 contains 4 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains. Human Contactin-3 shares 92 % aa identity with mouse Contactin-3.The exact function of Contactin-3 is unclear. Contactin-3 may mediate cell-cell interaction and may promote neurite outgrowth.

    Synonym: CNTN3

    分子量
    134.8 kDa
    NCBI登录号
    NP_062202
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