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C1QBP Protein (His tag)

C1QBP 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 92 % as determined by SDS-PAGE
产品编号 ABIN7320370
发货至: 中国
  • 抗原 See all C1QBP 蛋白
    C1QBP (Complement Component 1, Q Subcomponent Binding Protein (C1QBP))
    蛋白类型
    Recombinant
    宿主
    • 7
    • 3
    • 2
    • 2
    • 1
    小鼠
    资源
    • 10
    • 3
    • 2
    大肠杆菌(E. Coli)
    标记
    This C1QBP protein is labelled with His tag.
    原理
    Recombinant Mouse C1QBP Protein (His Tag)
    序列
    Leu 72-Gln 279
    产品特性
    A DNA sequence encoding the mature form of mouse C1QBP (NP_031599.2) (Leu 72-Gln 279) was expressed, with a polyhistide tag at the N-terminus.
    纯度
    > 92 % as determined by SDS-PAGE
    Top Product
    Discover our top product C1QBP 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    C1QBP (Complement Component 1, Q Subcomponent Binding Protein (C1QBP))
    别名
    C1QBP (C1QBP 产品)
    别名
    SF2 Protein, X38k Protein, gC1qR Protein, C1QBP Protein, GC1QBP Protein, HABP1 Protein, SF2p32 Protein, gC1Q-R Protein, p32 Protein, AA407365 Protein, AA986492 Protein, D11Wsu182e Protein, P32 Protein, gC1qBP Protein, Habp1 Protein, complement C1q binding protein Protein, complement component 1, q subcomponent binding protein S homeolog Protein, complement component 1, q subcomponent binding protein Protein, C1QBP Protein, c1qbp.S Protein, LOC100227158 Protein, C1qbp Protein
    背景

    Background: Hyaluronan binding protein 1 (HABP1), also known as p32 or gC1qR, is a ubiquitously expressed multifunctional phospho-protein implicated in cell signalling. Hyaluronan-binding protein 1 (HABP1) /p32/gC1qR was characterized as a highly acidic and oligomeric protein, which binds to different ligands like hyaluronan, C1q, and mannosylated albumin. The role of hyaluronan binding protein 1 (HABP1) in cell signaling was investigated and in vitro. HABP1 overexpressing cells showed extensive vacuolation and reduced growth rate, which was corrected by frequent medium replenishment. Further investigation revealed that HABP1 overexpressing cells undergo apoptosis, and they failed to enter into the S-phase. The sperm surface HABP1 level can be correlated with the degree of sperm motility.Hyaluronan binding protein 1 (HABP1) was reported to be present on human sperm surface and its involvement in fertilization has already been elucidated: decreased HABP1 level may be associated with low motility of sperms, which in turn might cause infertility in the patient. HABP1 also is an endogenous substrate for MAP kinase and upon mitogenic stimulation it is translocated to the nucleus in a MAP kinase-dependent manner.

    Synonym: AA407365,AA986492,D11Wsu182e,gC1qBP,HABP1,P32

    分子量
    24.7 kDa
    NCBI登录号
    NP_031599
    途径
    Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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