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COL4a3 Protein (Fc Tag)

COL4A3 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
产品编号 ABIN7321080
发货至: 中国
  • 抗原 See all COL4a3 (COL4A3) 蛋白
    COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 1
    大鼠
    资源
    • 2
    • 1
    HEK-293 Cells
    标记
    This COL4a3 protein is labelled with Fc Tag.
    原理
    Recombinant Rat COL4A3 Protein (Fc Tag)
    序列
    Gly1426-His1670
    产品特性
    A DNA sequence encoding the rat COL4A3 (NP_001129231) (Gly1426-His1670) was expressed with Fc region of human IgG1 at the N-terminus.
    纯度
    > 85 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))
    别名
    COL4A3 (COL4A3 产品)
    别名
    zTumstatin Protein, [a]3(IV) Protein, alpha3(IV) Protein, collagen type IV alpha 3 chain Protein, collagen, type IV, alpha 3 Protein, COL4A3 Protein, col4a3 Protein, Col4a3 Protein
    背景

    Background: COL4A3 is a major structural component of basement membranes. It is composed of 3 alpha subunits, which are encoded by 6 different genes, alpha 1 through alpha 6. Each of these alpha subunits can form a triple helix structure with 2 other subunits to form COL4A3. Autoantibodies bind to the collagen molecules in the basement membranes of alveoli and glomeruli can cause goodpasture syndrome. COL4A3 is also linked to an autosomal recessive form of alport syndrome. COL4A3 is organized in a head-to-head conformation and each gene pair shares a common promoter.

    Synonym: COL4A3

    分子量
    55.2 kDa
    NCBI登录号
    NP_001129231
    途径
    Sensory Perception of Sound, Positive Regulation of Endopeptidase Activity
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