CNDP2 Protein (His tag)
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- 抗原 See all CNDP2 蛋白
- CNDP2 (CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 小鼠
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资源
- Baculovirus infected Insect Cells
- 标记
- This CNDP2 protein is labelled with His tag.
- 原理
- Recombinant Mouse CNDP2/CPGL/PEPA Protein (His Tag)(Active)
- 序列
- Met 1-Asn 475
- 产品特性
- A DNA sequence encoding the mouse CNDP2 (NP_075638.2) (Met 1-Asn 475) was expressed, with a C-terminal polyhistidine tag.
- 纯度
- > 97 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to cleave carnosine (β-Ala-His) in a two step assay (mouse CNDP2 concentration 10 μg/ml). The specific activity is >40 pmoles/min/μg.
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- Discover our top product CNDP2 蛋白
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CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2) (AA 1-475) protein (His tag)
CNDP2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2) (AA 1-475) protein (GST tag)CNDP2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2) (AA 191-300) protein (GST tag)CNDP2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2) protein (His tag)CNDP2 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2) (AA 2-475) protein (His tag)Crystallography grade CNDP2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2) (AA 2-475) protein (His tag)Crystallography grade CNDP2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 50 mM Tris, 100 mM NaCl, 0.5 mM PMSF, 10 % glycerol, pH 8.5
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CNDP2 (CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2))
- 别名
- CNDP2/CPGL/PEPA (CNDP2 产品)
- 别名
- 0610010E05Rik Protein, C76600 Protein, Cn2 Protein, Dip-2 Protein, Pep-1 Protein, Pep1 Protein, CN2 Protein, CPGL Protein, HsT2298 Protein, PEPA Protein, cn2 Protein, cpgl Protein, darmin-r Protein, CNDP2 Protein, zgc:92569 Protein, wu:fd20d11 Protein, wu:fe17f09 Protein, cndp2b Protein, PEPC1 Protein, PEPCase Protein, PPC1 Protein, PPEPC4 Protein, pepc Protein, carnosine dipeptidase 2 Protein, CNDP dipeptidase 2 (metallopeptidase M20 family) Protein, CNDP dipeptidase 2 (metallopeptidase M20 family) S homeolog Protein, CNDP dipeptidase 2 (metallopeptidase M20 family) L homeolog Protein, phosphoenolpyruvate carboxylase 1 Protein, Cndp2 Protein, CNDP2 Protein, cndp2 Protein, cndp2.S Protein, cndp2.L Protein, pep1 Protein
- 背景
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Background: Cytosolic non-specific dipeptidase, also known as CNDP dipeptidase 2, Glutamate carboxypeptidase-like protein 1, Peptidase A, CNDP2 and CN2, is a cytoplasm protein which belongs to the peptidase M20A family. CNDP2 / CPGL is a cytosolic enzyme that can hydrolyze carnosine to yield l-histidine and beta-alanine. CNDP2 / CPGL hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. It may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells. Isoform 1 of CNDP2 / CPGL is ubiquitously expressed with higher levels in kidney and liver (at protein level). Isoform 2 of CNDP2 / CPGL is expressed in fetal tissues, it is only expressed in adult liver and placental tissues. CNDP2 / CPGL is highly expressed in the histaminergic neurons in the tuberomammillary nucleus, implying that it may supply histidine to histaminergic neurons for histamine synthesis.
Synonym: CNDP2;CNDP dipeptidase 2;Cytosolic non-specific dipeptidase;Glutamate carboxypeptidase-like protein 1;Dip-2;Pep-1;Pep1
- 分子量
- 54 kDa
- NCBI登录号
- NP_075638
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