CNTF Receptor alpha Protein (His tag)
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- 抗原 See all CNTF Receptor alpha (CNTFR) 蛋白
- CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 大鼠
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资源
- Baculovirus infected Insect Cells
- 标记
- This CNTF Receptor alpha protein is labelled with His tag.
- 原理
- Recombinant Rat CNTFR/CNTFR-alpha Protein (His Tag)(Active)
- 序列
- Met 1-Pro 346
- 产品特性
- A DNA sequence encoding the rat CNTFR (Q08406-1) (Met 1-Pro 346) was fused with a C-terminal polyhistidine tag.
- 纯度
- > 97 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized Rat CTNFR at 10 μg/ml (100 μl/well) can bind biotinylated human CNTF with a linear ranger of 1.28-160 ng/ml.
- Top Product
- Discover our top product CNTFR 蛋白
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Ciliary Neurotrophic Factor Receptor (CNTFR) (AA 47-158) protein (GST tag)
CNTFR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Ciliary Neurotrophic Factor Receptor (CNTFR) (AA 23-346) protein (His tag)CNTFR 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Ciliary Neurotrophic Factor Receptor (CNTFR) (AA 23-342) protein (His tag)CNTFR 宿主: 大鼠 宿主: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 8.0
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))
- 别名
- CNTFR/CNTFR-alpha (CNTFR 产品)
- 别名
- CNTFR-alpha Protein, CNTFRALPHA Protein, Cntfralpha Protein, cb549 Protein, fj33e02 Protein, sb:cb549 Protein, wu:fj33e02 Protein, si:bz76a6.1 Protein, si:dz248f2.1 Protein, si:rp71-76a6.1 Protein, ciliary neurotrophic factor receptor Protein, ciliary neurotrophic factor receptor L homeolog Protein, CNTFR Protein, cntfr.L Protein, Cntfr Protein, cntfr Protein
- 背景
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Background: Ciliary neurotrophic factor(CNTF) is a member of the cytokine family. It is a polypeptide hormone that have functions in promoting neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. It's actions appear to be restricted to the nervous system. Ciliary neurotrophic factor(CNTF) has biological effects through the activation of a multi-subunit receptor complex, consisting of an extracelluar CNTF binding subunit(CNTFα) and two transmembrane signal transduction proteins: glycoprotein gp130 and LIF receptor. CNTF is considered as a potent survival factor of neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. CNTF is also a survival factor for neurons of the peripheral sensory sympathetic, and ciliary ganglia. It has been reported that CNTF could be an agent that has therapeutic potential and possibly induces differentiation of large multipolar ganglionic phenotype in a subset of progenitors.
Synonym: Cntfr
- 分子量
- 39.6 kDa
- 途径
- JAK/STAT Signaling, Feeding Behaviour
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