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C12orf53 Protein (Fc Tag)

C12orf53 宿主: 人 宿主: HEK-293 Cells Recombinant > 96 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317278
发货至: 中国
  • 抗原 See all C12orf53 蛋白
    C12orf53 (Chromosome 12 Open Reading Frame 53 (C12orf53))
    蛋白类型
    Recombinant
    宿主
    • 2
    • 2
    资源
    • 4
    HEK-293 Cells
    标记
    This C12orf53 protein is labelled with Fc Tag.
    原理
    Recombinant Human C12orf53 Protein (Fc Tag)
    序列
    Met 1-Pro178
    产品特性
    A DNA sequence encoding the human C12orf53 (Q8IYJ0-1) (Met1-Pro178) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
    纯度
    > 96 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product C12orf53 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    C12orf53 (Chromosome 12 Open Reading Frame 53 (C12orf53))
    别名
    C12orf53 (C12orf53 产品)
    别名
    C12orf53 Protein, PANP Protein, leda-1 Protein, PILR alpha associated neural protein Protein, PIANP Protein
    背景

    Background: C12orf53 is mainly expressed in adult brain and cerebellum. It also can be detected in fetal brain and virtually no expression in spleen, heart, kidney, liver and dorsal ganglion relative to brain. C12orf53 acts as a ligand for PILRA in neural tissues, where it may be involved in immune regulation. Chromosome 12 encodes over 1,100 genes within 132 million bases. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC class I interaction.

    Synonym: C12orf53,leda-1,LEDA1,PANP,UNQ828/PRO1755

    分子量
    42.3 kDa
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