CHI3L2 Protein (His tag)
-
- 抗原 See all CHI3L2 蛋白
- CHI3L2 (Chitinase 3-Like 2 (CHI3L2))
- 蛋白类型
- Recombinant
- 宿主
- 人
-
资源
- 人细胞
- 标记
- This CHI3L2 protein is labelled with His tag.
- 原理
- Recombinant Human CHI3L2/YKL-39 Protein (His Tag)
- 序列
- Tyr27-Leu390
- 产品特性
- Recombinant Human Chitinase 3-Like Protein 2 is produced by our Mammalian expression system and the target gene encoding Tyr27-Leu390 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CHI3L2 蛋白
-
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- 抗原
- CHI3L2 (Chitinase 3-Like 2 (CHI3L2))
- 别名
- CHI3L2/YKL-39 (CHI3L2 产品)
- 别名
- CHIL2 Protein, YKL-39 Protein, YKL39 Protein, chitinase 3 like 2 Protein, CHI3L2 Protein
- 背景
-
Background: Chitinase 3-Like Protein 2 (CHI3L2) is a 39 kDa secreted glycoprotein which belongs to the glycosyl hydrolase 18 family and the most closely related to human cartilage glycoprotein 39, which promotes the growth of human synovial cells as well as skin and fetal lung fibroblasts. Highest expression of CHI3L2 is in chondrocytes, followed by synoviocytes, lung and heart. It is not detected in spleen, pancreas, and liver. CHI3L2 may also be expressed in developing brain and placenta. Increased levels of CHI3L2 have been demonstrated in synovial fluids of patients with rheumatoid or osteoarthritis as well as in some other pathologies and in malignant tumors, particularly in glioblastomas. CHI3L2 may bind glycan structure with high affinity, but not heparin. It has has no chitotriosidase activity, but is likely to bind some type of glycan.
Synonym: Chitinase-3-Like Protein 2, Chondrocyte Protein 39, YKL-39, CHI3L2,CHIL2,YKL-39,YKL39
- 分子量
- 41.94 kDa
- UniProt
- Q15782
-