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CXCR4 Protein (His tag)

CXCR4 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant >95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319956
发货至: 中国
  • 抗原 See all CXCR4 蛋白
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    蛋白类型
    Recombinant
    宿主
    • 13
    • 4
    • 2
    • 1
    资源
    • 9
    • 4
    • 3
    • 2
    大肠杆菌(E. Coli)
    标记
    This CXCR4 protein is labelled with His tag.
    原理
    Recombinant Human CXCR4 (C28A) Protein (His Tag)
    序列
    1M-38K
    产品特性
    A DNA sequence encoding the human CXCR4 (C28A) (1M-38K) was expressed with a GST tag at the N-terminus.
    纯度
    >95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product CXCR4 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile potassium phosphate, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    别名
    CXCR4 (CXCR4 产品)
    别名
    CD184 Protein, D2S201E Protein, FB22 Protein, HM89 Protein, HSY3RR Protein, LAP3 Protein, LCR1 Protein, LESTR Protein, NPY3R Protein, NPYR Protein, NPYRL Protein, NPYY3R Protein, WHIM Protein, Cmkar4 Protein, PB-CKR Protein, PBSF/SDF-1 Protein, Sdf1r Protein, CXC-R4-B Protein, CXCR-4-B Protein, cd184 Protein, cxcr4 Protein, fb22 Protein, hm89 Protein, hsy3rr Protein, lap3 Protein, lcr1 Protein, lestr Protein, npy3r Protein, npyr Protein, npyrl Protein, npyy3r Protein, xcxcr4 Protein, CXC-R4 Protein, CXCR-4 Protein, d2s201e Protein, whim Protein, CXC-R4-A Protein, CXCR-4-A Protein, xCXCR4 Protein, CXCR4 Protein, cb403 Protein, zgc:109863 Protein, cb824 Protein, C-X-C motif chemokine receptor 4 Protein, chemokine (C-X-C motif) receptor 4 Protein, C-X-C motif chemokine receptor 4 S homeolog Protein, C-X-C chemokine receptor type 4 Protein, C-X-C motif chemokine receptor 4 L homeolog Protein, chemokine (C-X-C motif), receptor 4b Protein, chemokine (C-X-C motif) receptor 4a Protein, CXCR4 Protein, Cxcr4 Protein, cxcr4.S Protein, cxcr4 Protein, LOC100049444 Protein, cxcr4.L Protein, cxcr4b Protein, cxcr4a Protein
    背景

    Background: Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ions levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin, leading to enhance intracellular calcium ions and reduce cellular cAMP levels. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Could be involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates. Promotes Env-mediated fusion of the virus.

    Synonym: C-X-C chemokine receptor type 4, CD184, FB22, Fusin, HM89, HSY3RR, LAP3, LCR1, NPYR, SDF 1 receptor, WHIM

    分子量
    31.2kDa
    UniProt
    P61073
    途径
    Regulation of Cell Size, CXCR4-mediated Signaling Events
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