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CCL8 Protein (His tag)

CCL8 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7320488
发货至: 中国
  • 抗原 See all CCL8 蛋白
    CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))
    蛋白类型
    Recombinant
    宿主
    • 13
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    小鼠
    资源
    • 23
    • 3
    • 2
    • 2
    人细胞
    标记
    This CCL8 protein is labelled with His tag.
    原理
    Recombinant Mouse CCL8/MCP-2 Protein (His Tag)
    序列
    Glu20-Pro97
    产品特性
    Recombinant Mouse C-C motif Chemokine 8 is produced by our Mammalian expression system and the target gene encoding Glu20-Pro97 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CCL8 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM Hac-NaC,150 mM NaCl, pH 4.0.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))
    别名
    CCL8/MCP-2 (CCL8 产品)
    别名
    HC14 Protein, MCP-2 Protein, MCP2 Protein, SCYA10 Protein, SCYA8 Protein, 1810063B20Rik Protein, AB023418 Protein, Mcp2 Protein, Scya8 Protein, C-C motif chemokine ligand 8 Protein, chemokine (C-C motif) ligand 8 Protein, C-C motif chemokine 8 Protein, monocyte chemoattractant protein-2 precursor Protein, CCL8 Protein, Ccl8 Protein, LOC101119572 Protein, MCP-2 Protein
    背景

    Background: Chemokine ligand 8 (CCL8,MCP-2), is a small secreted cytokine which belongs to the intercrine beta (chemokine CC) family. CCL8 Chemotactic factor attracts monocytes. It can bind heparin.CCL8 functions to activate different immune cells, including mast cells, eosinophils and basophils which are involved in allergic responses, monocytes, and T cells and NK cells which are involved in the inflammatory response. Its ability achieves by binding to different cell surface receptors termed chemokine receptors including CCR1, CCR2B and CCR5. It has been reported that CCL8 is a potent inhibitor of HIV-1 by virtue of its binding to CCR5 which is one of the major co-receptors for HIV-1.

    Synonym: C-C motif chemokine 8,Ccl8,Monocyte chemoattractant protein 2,Monocyte chemotactic protein 2,MCP-2,Small-inducible cytokine A8,Mcp2, Scya8

    分子量
    9.8 kDa
    UniProt
    Q9Z121
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