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CCL22 Protein (His tag)

CCL22 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
产品编号 ABIN7195054
发货至: 中国
  • 抗原 See all CCL22 蛋白
    CCL22 (Chemokine (C-C Motif) Ligand 22 (CCL22))
    蛋白类型
    Recombinant
    宿主
    • 14
    • 6
    • 4
    • 1
    • 1
    • 1
    资源
    • 20
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This CCL22 protein is labelled with His tag.
    原理
    Recombinant Human CCL22/MDC Protein (His Tag)
    序列
    Gly 25-Gln 93
    产品特性
    A DNA sequence encoding the secreeted form of human CCL22 (O00626) (Gly 25-Gln 93) was expressed, with a polyhistidine tag at the N-terminus.
    纯度
    > 90 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product CCL22 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile 30 % Acetonitrile, 0.1 % TFA
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CCL22 (Chemokine (C-C Motif) Ligand 22 (CCL22))
    别名
    CCL22/MDC (CCL22 产品)
    别名
    ABCD-1 Protein, DC/B-CK Protein, MDC Protein, SCYA22 Protein, STCP-1 Protein, DCBCK Protein, Scya22 Protein, Mdc Protein, CCL22 Protein, C-C motif chemokine ligand 22 Protein, chemokine (C-C motif) ligand 22 Protein, CCL22 Protein, Ccl22 Protein
    背景

    Background: Chemokine (C-C motif) ligand 22(ABCD-1 / CCL22)is a kind of CC chemokine which is a family of secreted proteins involved in immunoregulatory and inflammatory processes. The cytokine displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. This ABCD-1 / CCL22 chemokine binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated / effector T lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. ABCD-1 / CCL22 is highly expressed in macrophage and in monocyte-derived dendritic cells, and thymus, and in Langerhans' cell histiocytosis and atopic dermatitis but not in dermatopathic lymphadenopathy. This chemokine is also found in lymph node, appendix, activated monocytes, resting and activated macrophages. This protein is lower expressed in lung and spleen and very weekly expressed in small intestine.

    Synonym: A-152E5.1,ABCD-1,DC/B-CK,MDC,SCYA22,STCP-1

    分子量
    9.7 kDa
    UniProt
    O00626
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