CER1 Protein (His tag)
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- 抗原 See all CER1 蛋白
- CER1 (Cerberus 1 Homolog (Xenopus Laevis) (CER1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This CER1 protein is labelled with His tag.
- 原理
- Recombinant Human Cerberus/CER1 Protein (His Tag)
- 序列
- Thr18-Ala267
- 产品特性
- Recombinant Human Cerberus 1 is produced by our Mammalian expression system and the target gene encoding Thr18-Ala267 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CER1 蛋白
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Cerberus 1 Homolog (Xenopus Laevis) (CER1) (AA 1-267) protein (GST tag)
CER1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cerberus 1 Homolog (Xenopus Laevis) (CER1) (AA 158-266) protein (GST tag)CER1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cerberus 1 Homolog (Xenopus Laevis) (CER1) (AA 18-267) protein (His tag)Crystallography grade CER1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Cerberus 1 Homolog (Xenopus Laevis) (CER1) (AA 18-272) protein (His tag)Crystallography grade CER1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM HAc.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CER1 (Cerberus 1 Homolog (Xenopus Laevis) (CER1))
- 别名
- Cerberus/CER1 (CER1 产品)
- 别名
- DAND4 Protein, CAR Protein, cer Protein, cer-1 Protein, dand4 Protein, tCerberus Protein, xcer-1 Protein, xcer1 Protein, Cerl Protein, Cerl1 Protein, Cerr1 Protein, RGD1563046 Protein, cerberus 1, DAN family BMP antagonist Protein, cerberus 1, DAN family BMP antagonist S homeolog Protein, CER1 Protein, cer1.S Protein, Cer1 Protein
- 背景
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Background: Cerberus 1 is a secreted glycoprotein that forms disulfide-linked homodimers. It is a cytokine member of the DAN domain family of BMP antagonists that includes DAN (DAND1), Gremlin/Drm (DAND2), PRDC (Protein Related to Dan and Cerberus, DAND3), and COCO/Dante (DAND5). DAN family members contain a cysteine knot domain that is homologous to that found in other TGF-beta superfamily ligands. At the onset of gastrulation, Cerberus 1 is transiently expressed in anterior endodermal structures in response to Nodal and Shh. Cerberus 1 binds BMP-4 and Nodal and inhibits their activities. The inhibitory functions of Cerberus favor mesodermal development in the anterior region of the gastrula and suppresses posterior mesodermal differentiation. In chick and Xenopus, Cerberus 1 also regulates, but is not required for embryonic left-right polarization, neurulation, and head and heart induction.
Synonym: Cerberus, Cerberus-Related Protein, DAN Domain Family Member 4, CER1, DAND4
- 分子量
- 29.2 kDa
- UniProt
- O95813
- 途径
- Maintenance of Protein Location
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