CRABP2 Protein (His tag)
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- 抗原 See all CRABP2 蛋白
- CRABP2 (Cellular Retinoic Acid Binding Protein 2 (CRABP2))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- 大肠杆菌（E. Coli）
- 标记
- This CRABP2 protein is labelled with His tag.
- 原理
- Recombinant Mouse CRABP2 Protein (His Tag)
- 序列
- Pro 2-Glu 138
- 产品特性
- A DNA sequence encoding the mouse CRABP2 (P22935) (Pro 2-Glu 138) was expressed, with a polyhistide tag at the N-terminus.
- 纯度
- > 96 % as determined by SDS-PAGE
- Top Product
- Discover our top product CRABP2 蛋白
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Cellular Retinoic Acid Binding Protein 2 (CRABP2) (AA 2-138) protein (His tag)
CRABP2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Cellular Retinoic Acid Binding Protein 2 (CRABP2) (AA 1-138) protein (GST tag)CRABP2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cellular Retinoic Acid Binding Protein 2 (CRABP2) (AA 1-138) protein (Strep Tag)Crystallography grade CRABP2 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Cellular Retinoic Acid Binding Protein 2 (CRABP2) protein (Myc-DYKDDDDK Tag)CRABP2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CRABP2 (Cellular Retinoic Acid Binding Protein 2 (CRABP2))
- 别名
- CRABP2 (CRABP2 产品)
- 别名
- crabp Protein, crabp2-A Protein, xCRABP Protein, xCRABP-b Protein, cb432 Protein, cb434 Protein, crabp2 Protein, sb:cb434 Protein, wu:fc51a11 Protein, zgc:110496 Protein, CRABP2 Protein, rbp6 Protein, MGC89469 Protein, crabp-ii Protein, CRABP-II Protein, RBP6 Protein, AI893628 Protein, Crabp-2 Protein, CrabpII Protein, im:7136989 Protein, cellular retinoic acid binding protein 2 L homeolog Protein, cellular retinoic acid binding protein 2, a Protein, cellular retinoic acid binding protein 2 Protein, cellular retinoic acid binding protein II Protein, cellular retinoic acid binding protein 2, b Protein, crabp2.L Protein, crabp2a Protein, CRABP2 Protein, crabp2 Protein, Crabp2 Protein, crabp2b Protein
- 背景
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Background: Cellular retinoic acid-binding protein 2, also known as Cellular retinoic acid-binding protein II, CRABP-II and CRABP2, is a protein which belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. Cellular retinoic acid binding proteins (CRABP) are low molecular weight proteins whose precise function remains unknown. The predicted amino acid sequences of human CRABP1 and CRABP2 demonstrated a 99.3% and 93.5% identity to mouse CRABP1 and CRABP2, respectively. CRABP2 forms a beta-barrel structure that accommodates hydrophobic ligands in its interior. Expression of CRABP2, but not CRABP1 mRNA, was markedly increased (greater than 15-fold) by retinoic acid treatment of fibroblasts cultured from human skin, whereas no significant induction of CRABP2 mRNA was observed in human lung fibroblasts. CRABP2 transports retinoic acid to the nucleus. It regulates the access of retinoic acid to the nuclear retinoic acid receptors. CRABP2 is necessary for elastin induction by All-trans retinoic acid (ATRA) in MRC-5 cells. It is expressed at low levels in emphysema fibroblasts. This alteration in the retinoic acid signalling pathway in lung fibroblasts may contribute to the defect of alveolar repair in human pulmonary emphysema.
Synonym: AI893628;Crabp-2;CrabpII
- 分子量
- 17.1 kDa
- UniProt
- P22935
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