CREG1 Protein (His tag)
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- 抗原 See all CREG1 蛋白
- CREG1 (Cellular Repressor of E1A-Stimulated Genes 1 (CREG1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This CREG1 protein is labelled with His tag.
- 原理
- Recombinant Human CREG/CREG1 Protein (His Tag)
- 序列
- Arg32-Gln220
- 产品特性
- Recombinant Human CREG is produced by our Mammalian expression system and the target gene encoding Arg32-Gln220 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CREG1 蛋白
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Cellular Repressor of E1A-Stimulated Genes 1 (CREG1) protein (His tag)
CREG1 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Cellular Repressor of E1A-Stimulated Genes 1 (CREG1) (AA 30-220) protein (His tag)CREG1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Cellular Repressor of E1A-Stimulated Genes 1 (CREG1) (AA 32-220) protein (His tag)CREG1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Cellular Repressor of E1A-Stimulated Genes 1 (CREG1) (AA 121-220) protein (GST tag)CREG1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cellular Repressor of E1A-Stimulated Genes 1 (CREG1) protein (Fc Tag)CREG1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Cellular Repressor of E1A-Stimulated Genes 1 (CREG1) (AA 32-220) protein (His tag)Crystallography grade CREG1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Cellular Repressor of E1A-Stimulated Genes 1 (CREG1) (AA 32-220) protein (His tag)Crystallography grade CREG1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CREG1 (Cellular Repressor of E1A-Stimulated Genes 1 (CREG1))
- 别名
- CREG/CREG1 (CREG1 产品)
- 别名
- CREG1 Protein, CREG Protein, AA755314 Protein, Creg Protein, cellular repressor of E1A stimulated genes 1 Protein, cellular repressor of E1A-stimulated genes 1 Protein, CREG1 Protein, creg1 Protein, Creg1 Protein
- 背景
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Background: Cellular repressor of E1A genes (CREG) is an evolutionarily conserved lysosomal protein, and an important new factor in regulating tissue homeostasis that has been shown to antagonize injury of tissues or cells. CREG contains three mannose 6-phosphate (M6P) markers, and depends on interactions with M6P receptors for efficient delivery to lysosomes, which is implicated in the regulation of lysosomal functions. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. CREG plays an important role in the control of cell growth and differentiation. It has been shown that CREG antagonizes transcriptional and cellular transformation by the adenoviral E1A oncoprotein, induces differentiation while attenuating cellular proliferation, regulates the levels of the signaling kinases ERK1/2, and mediates glucocorticoid-induced proliferation of ileal epithelial cells. CREG is widely expressed in adult tissues, such as the brain, heart, lungs, liver, intestines and kidneys in mice, but is not markedly expressed in pluripotent embryonic stem cells.
Synonym: CREG1, cellular repressor of E1A-stimulated genes, cellular repressor of E1A-stimulated genes 1CREG, protein CREG1
- 分子量
- 21.9 kDa
- UniProt
- O75629
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