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CD5 Protein (CD5) (AA 24-370) (His tag)

CD5 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7320723
发货至: 中国
  • 抗原 See all CD5 蛋白
    CD5
    蛋白类型
    Recombinant
    产品特性
    AA 24-370
    宿主
    • 20
    • 7
    • 4
    • 2
    • 1
    小鼠
    资源
    • 21
    • 5
    • 3
    • 3
    • 2
    人细胞
    标记
    This CD5 protein is labelled with His tag.
    原理
    Recombinant Mouse CD5 Protein (aa 24-370, His Tag)
    序列
    Gln24-Asn370
    产品特性
    Recombinant Mouse T-Cell Surface Glycoprotein CD5 is produced by our Mammalian expression system and the target gene encoding Gln24-Asn370 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CD5 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CD5
    别名
    CD5 (CD5 产品)
    别名
    CD5 Protein, Ly-1 Protein, Ly-12 Protein, Ly-A Protein, Lyt-1 Protein, LEU1 Protein, T1 Protein, CD5 molecule Protein, CD5 antigen Protein, CD5 molecule like Protein, Cd5 molecule Protein, CD5 Protein, Cd5 Protein, CD5L Protein
    背景

    Background: CD5 is a transmembrane glycoprotein of the conserved scavenger receptor cysteine-rich (SRCR) superfamily and expressed on thymocytes, peripheral T cells and a subset of B cells (B1-a). Moreover, CD5 also was found expressed in small lymphocytic lymphoma, hairy cell leukaemia and mantle cell lymphoma cells. The long cytoplasmic tail of CD5 has no intrinsic enzymatic activity, but contains four tyrosine phosphorylation sites, including an immunoreceptor tyrosine-based (ITAM)-like motif (pseudo-ITAM) and an immunoreceptor tyrosine-based inhibitory (ITIM)-like motif (pseudo-ITIM), as well as multiple potential serine and threonine phosphorylation sites. It physically associates with the T cell antigen receptor (TCR) and B cell antigen receptor (BCR), where it negatively modulates the activation and differentiation signals transduced by these receptors. CD5 also plays an important role in protection from activation-induced cell death and in the recognition of pathogen associated molecular patterns (PAMPS) present on fungal surfaces.

    Synonym: T-cell surface glycoprotein CD5, CD5, CD5 antigen, CD5 antigen (p56-62), CD5 Molecule, LEU1T-cell surface glycoprotein CD5, Lymphocyte antigen T1,Leu-1, T1, Ly-1

    分子量
    38.9 kDa
    NCBI登录号
    NP_031676
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