CD226 Protein (CD226) (His tag)
Quick Overview for CD226 Protein (CD226) (His tag) (ABIN7317825)
抗原
See all CD226 蛋白蛋白类型
生物活性
宿主
资源
纯度
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标记
- This CD226 protein is labelled with His tag.
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原理
- Recombinant Human CD226/DNAM-1 Protein (His Tag)(Active)
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序列
- Met 1-Asn 247
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产品特性
- A DNA sequence encoding the human DNAM1 (NP_006557.2) extracellular domain (Met 1-Asn 247) was fused with a polyhistidine tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized human CD226 at 2 μg/ml (100 μl/well) can bind human CD112 with a linear ranger of 6.4-800 ng/ml.
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CD226 (CD226) (AA 19-247) protein (Fc Tag)
CD226 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD226 (CD226) (AA 19-247) protein (His-Avi Tag)CD226 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
CD226 (CD226) (AA 19-252) protein (His tag)CD226 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD226 (CD226) (AA 19-247) protein (His-Avi Tag,Biotin)CD226 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
CD226 (CD226) (AA 19-247) protein (mFc-His Tag)CD226 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
CD226 (CD226) (AA 19-252) (Active) protein (His tag)CD226 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
CD226 (CD226) protein (His tag)CD226 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
CD226 (CD226) (AA 19-247) protein (hIgG-His-tag)CD226 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS
CD226 (CD226) (Active) protein (His tag)CD226 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
CD226 (CD226) (Active) protein (Fc Tag)CD226 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD226
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别名
- CD226/DNAM-1
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背景
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Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD226; also known as PTA1 or DNAM-1; is a member of the immunoglobulin superfamily containing 2 Ig-like domains of the V-set. High rate of CD226 (Cluster of Differentiation 226) is found on the surface of natural killer cells; platelets; monocytes and a subset of T cells. CD226 have binding sites with CD112 and CD155 and mediate cellular adhesion to other cells containing its ligands.Immune CheckpointImmune Checkpoint Detection: ELISA Antibodies Immune Checkpoint Detection: FCM AntibodiesImmune Checkpoint ProteinsImmune Checkpoint Targets Co-stimulatory Immune Checkpoint Targets Immunotherapy Cancer Immunotherapy Targeted Therapy
Synonym: DNAM-1;DNAM1;PTA1;TLiSA1
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分子量
- 27.6 kDa
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NCBI登录号
- NP_006557
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
抗原
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