Cathepsin H Protein (CTSH) (AA 22-333) (His tag)
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- 抗原 See all Cathepsin H (CTSH) 蛋白
- Cathepsin H (CTSH)
- 蛋白类型
- Recombinant
- 产品特性
- AA 22-333
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宿主
- 小鼠
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资源
- 人细胞
- 标记
- This Cathepsin H protein is labelled with His tag.
- 原理
- Recombinant Mouse Cathepsin H/CTSH Protein (aa 22-333, His Tag)
- 序列
- Glu22-Val333
- 产品特性
- Recombinant Mouse Cathepsin H is produced by our Mammalian expression system and the target gene encoding Glu22-Val333 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CTSH 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- Cathepsin H (CTSH)
- 别名
- Cathepsin H/CTSH (CTSH 产品)
- 别名
- fc44c02 Protein, zgc:85774 Protein, wu:fc44c02 Protein, CTSH Protein, ACC-4 Protein, ACC-5 Protein, CPSB Protein, minichain Protein, AL022844 Protein, cathepsin H Protein, cathepsin H L homeolog Protein, ctsh Protein, CTSH Protein, ctsh.L Protein, Ctsh Protein
- 背景
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Background: Cathepsin H (CTSH), which can act both as an aminopeptidase and as an endopeptidase, is a lysosomal cysteine protease of the papain family. CTSH is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. CTSH is associated with various pathological conditions like human fibrous meningioma, colorectal cancer, arthritis, human prostate tumor and lung cancer. CTSH is associated with cancer progression because of their ability to degrade extracellular matrices facilitating invasion, angiogenesis and metastasis as is evident from numerous clinical reports and experimental models. The expression of CTSH is significantly increased in disease states such as in prostate tumors, sera of asthmatic patients, and mucosa of colorectal cancer patients.
Synonym: Pro-cathepsin H, CTSH, ACC-4, ACC-5, aleurain, cathepsin B3, cathepsin BA, cathepsin H, CPSB, minichain, N-benzoylarginine-beta-naphthylamide hydrolase
- 分子量
- 36.1 kDa
- 途径
- Positive Regulation of Endopeptidase Activity
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