CASP14 Protein (His tag)
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- 抗原 See all CASP14 蛋白
- CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This CASP14 protein is labelled with His tag.
- 原理
- Recombinant Human Caspase-14/CASP14 Protein (His Tag)(Active)
- 序列
- Ser 2-Gln 242
- 产品特性
- A DNA sequence encoding the human CASP14 (NP_036246.1) (Ser 2-Gln 242) was expressed, with a polyhistide tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Biological Activity Comment
- Measured by its ability to bind biotinylated Cynomolgus IL18 in a functional ELISA.
- Top Product
- Discover our top product CASP14 蛋白
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Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 133-242) protein (GST tag)
CASP14 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))
- 别名
- Caspase-14/CASP14 (CASP14 产品)
- 别名
- CASP14 Protein, MICE Protein, mini-ICE Protein, caspase 14, apoptosis-related cysteine peptidase Protein, caspase 14 Protein, caspase-14-like Protein, caspase-14 Protein, CASP14 Protein, Casp14 Protein, LOC485601 Protein, LOC780455 Protein
- 背景
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Background: Caspase 14 is a member of the caspase family. Caspases are a kind of cysteine proteinase consisting of a prodomain plus large and small catalytic subunits, that play a central role in cell apoptosis. Caspase 14 possesses an unusually short prodomain and is highly expressed in embryonic tissues but absent from most of the adult tissues except for the skin, which suggests a role in ontogenesis and skin physiology. Unlike the other short prodomain caspases(caspase-3, caspase-6, and caspase-7), Caspase 14 was not processed by multiple death stimuli including activation of members of the tumor necrosis factor receptor family and expression of proapaptotic members of the bcl-2 family. Caspase 14 has been described to be processed and activated by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may take part in keratinocyte terminal differentiation, which is essential for the skin barrier.
Synonym: Caspase-14, CASP-14, CASP14,MGC119078,MGC119079
- 分子量
- 28.5 kDa
- NCBI登录号
- NP_036246
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