CPT1B Protein (His tag)
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- 抗原 See all CPT1B 蛋白
- CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This CPT1B protein is labelled with His tag.
- 原理
- Recombinant Mouse MCPT1 Protein (His Tag)
- 序列
- Met 1-Lys 246
- 产品特性
- A DNA sequence encoding the mouse MCPT1 (NP_032596.1) (Met 1-Lys 246) was expressed with a polyhistidine tag at the C-terminus.
- 纯度
- > 97 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product CPT1B 蛋白
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Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B) (AA 673-772) protein (GST tag)
CPT1B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))
- 别名
- MCPT1 (CPT1B 产品)
- 别名
- CPT1-M Protein, CPT1M Protein, CPTI Protein, CPTI-M Protein, M-CPT1 Protein, MCCPT1 Protein, MCPT1 Protein, CPT-IB Protein, M-CPTI Protein, CPT1 Protein, CPTIB Protein, cpt1al Protein, zgc:103709 Protein, CPT1B Protein, MGC147544 Protein, Cpt1 Protein, Cpt1-m Protein, Cpti Protein, Cpti-m Protein, M-cpti Protein, carnitine palmitoyltransferase 1B Protein, carnitine palmitoyltransferase 1B (muscle) Protein, carnitine palmitoyltransferase 1B L homeolog Protein, carnitine palmitoyltransferase 1b, muscle Protein, CPT1B Protein, Cpt1b Protein, cpt1b Protein, cpt1b.L Protein
- 背景
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Background: Mast Cell Protease 1 (MMCP-1), also known as MCP-1, MCPT-1 and β-chymase, is a member of the Chymase family of chymotrypsin-like serine proteases. MCPT-1 is a 26 kDa β-chymase that is a component of mast cell granules. It is a 226 amino acid (aa) protein that has a conserved pattern of six cysteines and one potential glycosylation site. The granule-derived mouse mast cell proteases-1 and -2 (mMCP-1 and -2) colocalize in similar quantities in mucosal mast cells but micrograms of mMCP-1 compared with nanograms of mMCP-2 are detected in peripheral blood during intestinal nematode infection. mMCP-1 isolated from serum is complexed with serpins and both the accumulation and the longevity of mMCP-1 in blood is due to complex formation, protecting it from a pathway that rapidly clears mMCP-2, which is unable to form complexes with serpins. The mucosal mast cell (MMC) granule-specific beta-chymase, mouse mast cell protease-1 (mMCP-1), is released systemically into the bloodstream early in nematode infection before parasite-specific IgE responses develop and TGF-beta1 induces constitutive release of mMCP-1 by homologues of MMC in vitro. Expression of mMCP-1 is largely restricted to intraepithelial MMC and is thought to play a role in the regulation of epithelial permeability. Its activation is completed by the removal of a two residue N-terminal propeptide by a dipeptidyl peptidase (Cathepsin C). MCPT-1 is upregulated in the intestine in response to nematode infection, or in systemic mucosa in response to anaphylaxis. Like human α-chymase, MCPT-1 is capable of the conversion of angiotensin I to angiotensin II, which plays a key role in the regulation of arterial pressure. The intestinal inflammation associated with gastrointestinal helminths is partly mediated by mMCP-1.
Synonym: AV080368;Mcp-1
- 分子量
- 26.8 kDa
- NCBI登录号
- NP_032596
- 途径
- AMPK Signaling, Monocarboxylic Acid Catabolic Process
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