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CPM Protein (His tag)

CPM 宿主: 人 宿主: HEK-293 Cells Recombinant > 98 % as determined by reducing SDS-PAGE. Active
产品编号 ABIN7194614
发货至: 中国
  • 抗原 See all CPM 蛋白
    CPM (Carboxypeptidase M (CPM))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 7
    • 3
    • 1
    资源
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This CPM protein is labelled with His tag.
    原理
    Recombinant Human Carboxypeptidase M/CPM Protein (His Tag)(Active)
    序列
    Met 1-His 422
    产品特性
    A DNA sequence encoding the human CPM (NP_938079.1) without the propeptide (Met 1-His 422) was expressed, fused with a polyhistidine tag at the C-terminus.
    纯度
    > 98 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Measured by its ability to release Larginine from BenzoylAlaArg, with detection of the arginine amino group by ophthaldialdehyde.The specific activity is >40,000 pmoles/min/μg.
    Top Product
    Discover our top product CPM 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CPM (Carboxypeptidase M (CPM))
    别名
    Carboxypeptidase M/CPM (CPM 产品)
    别名
    im:7143022 Protein, im:7143022l Protein, si:dkey-11p6.1 Protein, zgc:110307 Protein, CPM Protein, 1110060I01Rik Protein, 5730456K23Rik Protein, AA589379 Protein, E030045M14Rik Protein, carboxypeptidase M Protein, carboxypeptidase D Protein, CPM Protein, cpm Protein, LOC5574253 Protein, Cpm Protein
    背景

    Background: Carboxypeptidase M, also known as CPM, is a membrane-bound arginine/lysine carboxypeptidase which is a member of the carboxypeptidases family. These enzymes remove C-terminal amino acids from peptides and proteins and exert roles in the physiological processes of blood coagulation/fibrinolysis, inflammation, food digestion and pro-hormone and neuropeptide processing. Among the carboxypeptidases CPM is of particular importance because of its constitutive expression in an active form at the surface of specialized cells and tissues in the human body. CPM in the brain appears to be membrane-bound via a phosphatidylinositol glycan anchor. CPM is widely distributed in a variety of tissues and cells. The amino acid sequence of CPM indicated that the C-terminal hydrophobic region might be a signal for membrane attachment via a glycosylphosphatidylinositol (GPI) anchor. CPM is involved in peptide metabolism on both the cell surface and in extracellular fluids. CPM functions not only as a protease but also as a binding partner in cell-surface protein-protein interactions.

    Synonym: Carboxypeptidase M,CPM

    分子量
    47.7 kDa
    NCBI登录号
    NP_938079
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