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CES2 Protein (His tag)

CES2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE Active
产品编号 ABIN7194592
发货至: 中国
  • 抗原 See all CES2 蛋白
    CES2 (Carboxylesterase 2 (CES2))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 7
    • 1
    小鼠
    资源
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This CES2 protein is labelled with His tag.
    原理
    Recombinant Mouse Carboxylesterase-2/CES2 Protein (His Tag)(Active)
    序列
    Met 1-Lys 557
    产品特性
    A DNA sequence encoding the extracellular domain of mouse CES2 (NP_663578.1) (Met 1-Lys 557) was expressed, with a polyhistidine tag at the C-terminus.
    纯度
    > 85 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Biological Activity Comment
    Measured by its ability to hydrolyze pnitrophenylacetate. The specific activity is >90,000 pmoles/min/μg.
    Top Product
    Discover our top product CES2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CES2 (Carboxylesterase 2 (CES2))
    别名
    Carboxylesterase-2/CES2 (CES2 产品)
    别名
    CE-2 Protein, CES2A1 Protein, PCE-2 Protein, iCE Protein, Ces2 Protein, im:6908784 Protein, si:dkey-38l12.2 Protein, zgc:153863 Protein, ce-2 Protein, ces2a1 Protein, pce-2 Protein, carboxylesterase 2 Protein, liver carboxylesterase 2 Protein, cocaine esterase Protein, carboxylesterase 2 (intestine, liver) Protein, CES2 Protein, Ces2 Protein, LOC100343300 Protein, LOC100734360 Protein, ces2 Protein
    背景

    Background: Carboxylesterase 2 (CES2) is a member of the carboxylesterase family and belongs to the multigene family. Carboxylesterase 2 is responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and beroin. It also serves to hydrolyze long-chain fatty acid esters and thioesters. It is speculated that carboxylesterases may play a role in lipid metabolism and the blood-brain barrier system and together with isform 1, are a serine esterase involved in both drug metabolism and activation. Human carboxylesterase 2 is commonly expressed in tumor tissues and irinotecan, a topoisomerase I inhibitor commonly used in the treatment of many solid tumors.

    Synonym: ces2A3

    分子量
    60.4 kDa
    NCBI登录号
    NP_663578
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