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CREB3L1 Protein (AA 396-519) (His tag)

CREB3L1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317341
发货至: 中国
  • 抗原 See all CREB3L1 蛋白
    CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))
    蛋白类型
    Recombinant
    产品特性
    AA 396-519
    宿主
    • 5
    • 3
    资源
    • 4
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This CREB3L1 protein is labelled with His tag.
    原理
    Recombinant Human CREB3L1/OASIS Protein (aa 396-519, His Tag)
    序列
    Glu396-Ser519
    产品特性
    A DNA sequence encoding the human CREB3L1 (Q96BA8-1) (Glu396-Ser519) was expressed with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CREB3L1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, PH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))
    别名
    CREB3L1/OASIS (CREB3L1 产品)
    别名
    CREB3L1 Protein, OASIS Protein, Oasis Protein, diacylglycerol kinase-like Protein, cAMP responsive element binding protein 3 like 1 Protein, cAMP responsive element binding protein 3-like 1 Protein, LOC423198 Protein, CREB3L1 Protein, Creb3l1 Protein
    背景

    Background: CREB3L1, also known as OASIS, is a cellular transcription factor synthesized as a membrane-bound precursor. It is a putative endoplasmic reticulum (ER) stress sensor in astrocytes with a mechanism of activation. OASIS mRNA expression was detected in pancreatic β-cell lines and rodent islets, and the expression level was up-regulated by ER stress-inducing compounds. CREB3L1 may have a role in pancreas development. CREB3L1 may also play an important role in limiting virus spread by inhibiting proliferation of virus-infected cells. In vitro, CREB3L1 binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE. It may play a role in gliosis.

    Synonym: OASIS,PSEC0238

    分子量
    15.2 kDa
    途径
    Thyroid Hormone Synthesis, Chromatin Binding
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