CREB3L1 Protein (AA 396-519) (His tag)
-
- 抗原 See all CREB3L1 蛋白
- CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 396-519
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This CREB3L1 protein is labelled with His tag.
- 原理
- Recombinant Human CREB3L1/OASIS Protein (aa 396-519, His Tag)
- 序列
- Glu396-Ser519
- 产品特性
- A DNA sequence encoding the human CREB3L1 (Q96BA8-1) (Glu396-Ser519) was expressed with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CREB3L1 蛋白
-
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, PH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- 抗原
- CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))
- 别名
- CREB3L1/OASIS (CREB3L1 产品)
- 别名
- CREB3L1 Protein, OASIS Protein, Oasis Protein, diacylglycerol kinase-like Protein, cAMP responsive element binding protein 3 like 1 Protein, cAMP responsive element binding protein 3-like 1 Protein, LOC423198 Protein, CREB3L1 Protein, Creb3l1 Protein
- 背景
-
Background: CREB3L1, also known as OASIS, is a cellular transcription factor synthesized as a membrane-bound precursor. It is a putative endoplasmic reticulum (ER) stress sensor in astrocytes with a mechanism of activation. OASIS mRNA expression was detected in pancreatic β-cell lines and rodent islets, and the expression level was up-regulated by ER stress-inducing compounds. CREB3L1 may have a role in pancreas development. CREB3L1 may also play an important role in limiting virus spread by inhibiting proliferation of virus-infected cells. In vitro, CREB3L1 binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE. It may play a role in gliosis.
Synonym: OASIS,PSEC0238
- 分子量
- 15.2 kDa
- 途径
- Thyroid Hormone Synthesis, Chromatin Binding
-