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CALML5 Protein (GST tag,His tag)

CALML5 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 92 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317487
发货至: 中国
  • 抗原 See all CALML5 蛋白
    CALML5 (Calmodulin-Like 5 (CALML5))
    蛋白类型
    Recombinant
    宿主
    • 6
    • 1
    • 1
    资源
    • 3
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This CALML5 protein is labelled with GST tag,His tag.
    原理
    Recombinant Human CALML5/CLSP Protein (His & GST Tag)
    序列
    Met 1-Glu 146
    产品特性
    A DNA sequence encoding the human CALML5 (AAH39172.1) (Met 1-Glu 146) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
    纯度
    > 92 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product CALML5 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile 20 mM Tris, 150 mM NaCl, 1 mM DTT, 0.5 mM GSH, 10 % glycerol, pH 7.8
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CALML5 (Calmodulin-Like 5 (CALML5))
    别名
    CALML5/CLSP (CALML5 产品)
    别名
    CALML5 Protein, CLSP Protein, F14B2.33 Protein, multicopy suppressors of snf4 deficiency in yeast 3 Protein, calmodulin like 5 Protein, calmodulin-like 5 Protein, Calcium-binding EF-hand family protein Protein, CALML5 Protein, MSS3 Protein
    背景

    Background: Calmodulin-like protein 5, also known as Calmodulin-like skin protein, CALML5 and CLSP, is a protein which contains four EF-hand domains. CALML5 / CLSP is particularly abundant in the epidermis where its expression is directly related to keratinocyte differentiation.The expression is very low in lung. CALML5 / CLSP binds calcium. It may be involved in terminal differentiation of keratinocytes. Coxsackievirus and adenovirus receptor (CAR) is a member of the immunoglobulin (Ig) superfamily and a component of epithelial tight junction. CAR functions as a primary receptor for coxsackievirus B and adenovirus (Ad) infection. CALML5 / CLSP is closely related to CAR. The structure and dynamics of human calmodulin-like skin protein CALML5 / CLSP have been characterized by NMR spectroscopy. The mobility of CALML5 / CLSP has been found to be different for the N-terminal and C-terminal domains. The N-terminal domain is characterized by four stable helices, which experience large fluctuations. This is shown to be due to mutations in the hydrophobic core. The overall N-terminal domain behavior is similar both in the full-length protein and in the isolated domain.

    Synonym: CLSP

    分子量
    44.2 kDa
    途径
    Phototransduction
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