CALCB Protein (Fc Tag)
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- 抗原 See all CALCB 蛋白
- CALCB (Calcitonin-Related Polypeptide beta (CALCB))
- 蛋白类型
- Recombinant
- 宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CALCB protein is labelled with Fc Tag.
- 原理
- Recombinant Human CALCB Protein (aa 1-118, Fc Tag)
- 序列
- Met 1-Phe118
- 产品特性
- A DNA sequence encoding the human CALCB (P10092) (Met1-Phe118) was fused with Fc region of mouse IgG at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product CALCB 蛋白
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Calcitonin-Related Polypeptide beta (CALCB) protein (Myc-DYKDDDDK Tag)
CALCB 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CALCB (Calcitonin-Related Polypeptide beta (CALCB))
- 别名
- CALCB (CALCB 产品)
- 别名
- CRSP Protein, CRSP-1 Protein, CRSP1 Protein, CALCB Protein, CALC2 Protein, CGRP-II Protein, CGRP2 Protein, Calc2 Protein, calcitonin-related polypeptide beta Protein, calcitonin related polypeptide beta Protein, calcitonin gene-related peptide 2 Protein, calcitonin-related polypeptide, beta Protein, CALCB Protein, LOC698209 Protein, Calcb Protein
- 背景
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Background: CALCB, also known as CGPR and calcitonin 2, belongs to the calcitonin family. CALCB is a calcitonin (CT) peptide which may play a role in the mediation of human inflammatory diseases. It is highly expressed in the skin, blood, and cerebrospinal fluid. CGRP immunolabeling (IL) was detected in epidermal keratinocytes at levels that were especially high and widespread in the skin of humans from locations afflicted with postherpetic neuralgia (PHN) and complex region pain syndrome type 1 (CRPS), of monkeys infected with simian immunodeficiency virus, and of rats subjected to L5/L6 spinal nerve ligation, sciatic nerve chronic constriction, and subcutaneous injection of complete Freund's adjuvant. Increased CGRP-IL was also detected in epidermal keratinocytes of transgenic mice with keratin-14 promoter driven overexpression of noggin, an antagonist to BMP-4 signaling. CGPR dilates a variety of vessels including the coronary, cerebral and systemic vasculature.
Synonym: Calcitonin gene-related peptide 2, CALC2, Beta-type CGRP, Calcitonin gene-related peptide II, CALCB
- 分子量
- 36.2 kDa
- UniProt
- P10092
- 途径
- Hormone Activity
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