C1D Protein (GST tag)
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- 抗原 See all C1D 蛋白
- C1D (C1D Nuclear Receptor Corepressor (C1D))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This C1D protein is labelled with GST tag.
- 原理
- Recombinant Human C1D Protein (GST Tag)
- 序列
- Met 1-Ser 141
- 产品特性
- A DNA sequence encoding the human C1D (Q13901) (Met 1-Ser 141) was fused with the GST tag at the N-terminus.
- 纯度
- > 80 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product C1D 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.5
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- C1D (C1D Nuclear Receptor Corepressor (C1D))
- 别名
- C1D (C1D 产品)
- 别名
- LRP1 Protein, SUN-CoR Protein, SUNCOR Protein, hC1D Protein, 1110036E10Rik Protein, AI875855 Protein, zgc:103509 Protein, RGD1560600 Protein, C1D nuclear receptor corepressor Protein, C1D nuclear receptor corepressor L homeolog Protein, C1D nuclear receptor co-repressor Protein, C1D Protein, c1d Protein, c1d.L Protein, C1d Protein
- 背景
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Background: C1D nuclear receptor corepressor belongs to the C1D family. It is a DNA binding and apoptosis-inducing protein.C1D nuclear receptor corepressorinteracts with TSNAX and DNA-PKcs. It acts as a corepressor for the thyroid hormone receptor. It is thought that C1D nuclear receptor corepressor regulates TRAX/Translin complex formation. It is expressed in kidney, heart, brain, spleen, lung, testis, liver and small intestine. It plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA, this function may include MPHOSPH6. It potentiates transcriptional repression by NR1D1 and THRB. C1D nuclear receptor corepressorcan activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. It also can induce apoptosis in a p53/TP53 dependent manner.
Synonym: hC1D,LRP1,Rrp47,SUN-CoR,SUNCOR
- 分子量
- 43.2 kDa
- UniProt
- Q13901
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