CLEC2D Protein (Fc Tag)
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- 抗原 See all CLEC2D 蛋白
- CLEC2D (C-Type Lectin Domain Family 2, Member D (CLEC2D))
- 蛋白类型
- Recombinant
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宿主
- 大鼠
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资源
- HEK-293 Cells
- 标记
- This CLEC2D protein is labelled with Fc Tag.
- 原理
- Recombinant Rat CLEC2D/OCIL Protein (Fc Tag)
- 序列
- Lys98-Leu233
- 产品特性
- A DNA sequence encoding the rat CLEC2D (NP_569086.1) (Lys98-Leu233) was expressed with Fc region of human IgG1 at the N-terminus.
- 纯度
- (76.7+14.8) % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method
- Top Product
- Discover our top product CLEC2D 蛋白
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C-Type Lectin Domain Family 2, Member D (CLEC2D) (AA 60-191) protein (Fc-Avi Tag)
CLEC2D 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
C-Type Lectin Domain Family 2, Member D (CLEC2D) (AA 60-191) protein (Fc-Avi Tag,Biotin)CLEC2D 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
C-Type Lectin Domain Family 2, Member D (CLEC2D) protein (His tag)CLEC2D 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % by SDS - PAGE SDS
C-Type Lectin Domain Family 2, Member D (CLEC2D) protein (Fc Tag)CLEC2D 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
C-Type Lectin Domain Family 2, Member D (CLEC2D) (AA 1-154) protein (GST tag)CLEC2D 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
C-Type Lectin Domain Family 2, Member D (CLEC2D) (AA 1-191) protein (Strep Tag)Crystallography grade CLEC2D 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
C-Type Lectin Domain Family 2, Member D (CLEC2D) (AA 1-207) protein (Strep Tag)Crystallography grade CLEC2D 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
C-Type Lectin Domain Family 2, Member D (CLEC2D) (AA 60-191) protein (His tag)Crystallography grade CLEC2D 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
C-Type Lectin Domain Family 2, Member D (CLEC2D) (AA 63-207) protein (His tag)Crystallography grade CLEC2D 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CLEC2D (C-Type Lectin Domain Family 2, Member D (CLEC2D))
- 别名
- CLEC2D/OCIL (CLEC2D 产品)
- 别名
- CLAX Protein, LLT1 Protein, OCIL Protein, Clr-b Protein, Clrb Protein, Ocil Protein, Clec2d5 Protein, CLEC2D Protein, C-type lectin domain family 2 member D Protein, C-type lectin domain family 2, member d Protein, C-type lectin domain family 2, member D Protein, CLEC2D Protein, Clec2d Protein
- 背景
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Background: Lectin-like transcript 1 (LLT1) encoded by CLEC2D gene is a C-type lectin-like molecule interacting with human CD161 (NKR-P1A) receptor expressed by natural killer cells and subsets of T cells. CLEC2D transcripts were detected primarily in hematopoietic cell lines and were found to be co-induced by the same activation signals. Although very low amounts of putative soluble CLEC2D protein isoforms could be produced by transfectants, CLEC2D isoforms 2 and 4 were efficiently expressed. CLEC2D uses gene splicing to generate protein isoforms that are structurally distinct and that have different biological activities. Prostate cancer is the most common type of cancer diagnosed and the second leading cause of cancer-related death in American men. Natural Killer (NK) cells are the first line of defense against cancer and infections. NK cell function is regulated by a delicate balance between signals received through activating and inhibitory receptors. Previously, we identified Lectin-like transcript-1 (LLT1/OCIL/CLEC2D) as a counter-receptor for the NK cell inhibitory receptor NKRP1A (CD161). Interaction of LLT1 expressed on target cells with NKRP1A inhibits NK cell activation.
Synonym: CLEC2D
- 分子量
- 44 kDa
- NCBI登录号
- NP_569086
- 途径
- Regulation of Leukocyte Mediated Immunity
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