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CLEC14A Protein (Fc Tag)

CLEC14A 宿主: 大鼠 宿主: HEK-293 Cells Recombinant (75.4+12.7) % as determined by SDS-PAGE
产品编号 ABIN7321192
发货至: 中国
  • 抗原 See all CLEC14A 蛋白
    CLEC14A (C-Type Lectin Domain Family 14, Member A (CLEC14A))
    蛋白类型
    Recombinant
    宿主
    • 6
    • 3
    大鼠
    资源
    • 4
    • 3
    • 1
    • 1
    HEK-293 Cells
    标记
    This CLEC14A protein is labelled with Fc Tag.
    原理
    Recombinant Rat CLEC14A/EGFR-5 Protein (Fc Tag)
    序列
    Met1-Thr398
    产品特性
    A DNA sequence encoding the rat CLEC14A (Met1-Thr398) was expressed with the Fc region of human IgG1 at the C-terminus.
    纯度
    (75.4+12.7) % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method
    Top Product
    Discover our top product CLEC14A 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CLEC14A (C-Type Lectin Domain Family 14, Member A (CLEC14A))
    别名
    CLEC14A/EGFR-5 (CLEC14A 产品)
    别名
    C14orf27 Protein, CEG1 Protein, EGFR-5 Protein, 1200003C23Rik Protein, AI642649 Protein, C-type lectin domain containing 14A Protein, C-type lectin domain family 14, member a Protein, CLEC14A Protein, Clec14a Protein
    背景

    Background: C-type lectin domain family 14 member A, also known as Epidermal growth factor receptor 5 and CLEC14A, is a member of the C-type lectin domain (CTLD) family that contains one c-type lectin domain and one EGF-like domain. Mouse CLEC14A is a 459 amino acid single-pass type I membrane protein. The superfamily of proteins containing C-type lectin-like domains (CTLDs) is a large group of extracellular Metazoan proteins with diverse functions. The CTLD structure has a characteristic double-loop ('loop-in-a-loop') stabilized by two highly conserved disulfide bridges located at the bases of the loops, as well as a set of conserved hydrophobic and polar interactions. Members of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily share a common fold and are involved in a variety of functions, such as generalized defense mechanisms against foreign agents, discrimination between healthy and pathogen-infected cells, and endocytosis and blood coagulation. Genome-level studies on human, elegans and melanogaster demonstrated almost complete divergence among invertebrate and mammalian families of CTLD-containing proteins (CTLDcps). The vertebrate CTLDcp families were essentially formed early in vertebrate evolution and are completely different from the invertebrate families. The composition of the CTLDcp superfamily in fish and mammals suggests that large scale duplication events played an important role in the evolution of vertebrates.

    Synonym: CLEC14A

    分子量
    67.6 kDa
    NCBI登录号
    NP_001014099
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