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BTN3A3 Protein (Fc Tag)

BTN3A3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317245
发货至: 中国
  • 抗原 See all BTN3A3 蛋白
    BTN3A3 (butyrophilin, Subfamily 3, Member A3 (BTN3A3))
    蛋白类型
    Recombinant
    宿主
    • 9
    • 1
    资源
    • 3
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This BTN3A3 protein is labelled with Fc Tag.
    原理
    Recombinant Human BTN3A3 Protein (Fc Tag)
    序列
    Met 1-Trp248
    产品特性
    A DNA sequence encoding the human BTN3A3 (O00478-1) (Met1-Trp248) was fused with Fc region of mouse IgG at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product BTN3A3 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    BTN3A3 (butyrophilin, Subfamily 3, Member A3 (BTN3A3))
    别名
    BTN3A3 (BTN3A3 产品)
    别名
    Btn3a3 Protein, EG632126 Protein, NG11 Protein, BTF3 Protein, butyrophilin-like 4 Protein, butyrophilin subfamily 3 member A3 Protein, butyrophilin, subfamily 3, member A3 Protein, Btnl4 Protein, BTN3A3 Protein
    背景

    Background: Tumor necrosis factor receptor superfamily, member 19 (TNFRSF19), also known as TAJ-alpha or TROY, is a member of the TNF-receptor superfamily. TNFRSF19/TROY expression is detected in the pulmonary epithelium and the ductal epithelium of the prostate and parotid glands. TNFRSF19/TROY expression is detected in some adenocarcinoma cell lines that arise from this tissue. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. TNFRSF19/TROY is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. TNFRSF19/TROY was negatively regulated by adipogenic transcription factor CCAAT/enhancer-binding proteins (C/EBP). TNFRSF19 signals activation of the Jnk pathway and induces cell death. Overexpression of TNFRSF19 also signals NFB activation, comparable and similar to that by p75NGFR. TNFRSF19/TROY is capable of activating key signaling pathways of the TNF receptor family, and its predominant expression patterns suggest that it plays a role in the growth and regulation of epithelial tissues.

    Synonym: Butyrophilin subfamily 3 member A3,BTN3A3,BTF3,BTN3.3

    分子量
    50 kDa
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