BBOX1 Protein (GST tag,His tag)
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- 抗原 See all BBOX1 蛋白
- BBOX1 (butyrobetaine (Gamma), 2-Oxoglutarate Dioxygenase (Gamma-butyrobetaine Hydroxylase) 1 (BBOX1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This BBOX1 protein is labelled with GST tag,His tag.
- 原理
- Recombinant Human BBOX1/Gamma-BBH Protein (His & GST Tag)
- 序列
- Met 1-Asn387
- 产品特性
- A DNA sequence encoding the human BBOX1 (O75936) (Met1-Asn387) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- 纯度
- > 85 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product BBOX1 蛋白
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butyrobetaine (Gamma), 2-Oxoglutarate Dioxygenase (Gamma-butyrobetaine Hydroxylase) 1 (BBOX1) (AA 1-387) protein (GST tag)
BBOX1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
butyrobetaine (Gamma), 2-Oxoglutarate Dioxygenase (Gamma-butyrobetaine Hydroxylase) 1 (BBOX1) (AA 278-387) protein (GST tag)BBOX1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
butyrobetaine (Gamma), 2-Oxoglutarate Dioxygenase (Gamma-butyrobetaine Hydroxylase) 1 (BBOX1) protein (Myc-DYKDDDDK Tag)BBOX1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 8.0
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- BBOX1 (butyrobetaine (Gamma), 2-Oxoglutarate Dioxygenase (Gamma-butyrobetaine Hydroxylase) 1 (BBOX1))
- 别名
- BBOX1/Gamma-BBH (BBOX1 产品)
- 别名
- BBOX1 Protein, wu:fj14g08 Protein, zgc:112179 Protein, BBH Protein, BBOX Protein, G-BBH Protein, gamma-BBH Protein, Bbh Protein, Bbox Protein, AI874739 Protein, gamma-butyrobetaine hydroxylase 1 Protein, butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 Protein, gamma-butyrobetaine dioxygenase Protein, butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase) Protein, BBOX1 Protein, bbox1 Protein, LOC699465 Protein, Bbox1 Protein
- 背景
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Background: BBOX1, also known as gamma-BBH, belongs to the gamma-BBH/TMLD family. It is highly expressed in kidney and moderately expressed in liver. BBOX1 catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation. BBOX1 is an inhibition target for mildronate which can be used to treat angina andmyocardial infarction. Mildronate may also be beneficial for the treatment ofneurological disorder, diabetes, and seizures and alcohol intoxication.
Synonym: BBH;BBOX;G-BBH;gamma-BBH
- 分子量
- 72.5 kDa
- UniProt
- O75936
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