BAI3 Protein (His tag)
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- 抗原 See all BAI3 蛋白
- BAI3 (Brain-Specific Angiogenesis Inhibitor 3 (BAI3))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This BAI3 protein is labelled with His tag.
- 原理
- Recombinant Human BAI3 Protein (His Tag)
- 序列
- Ala25-Thr880
- 产品特性
- Recombinant Human Brain-Specific Angiogenesis Inhibitor 3 is produced by our Mammalian expression system and the target gene encoding Ala25-Thr880 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product BAI3 蛋白
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Brain-Specific Angiogenesis Inhibitor 3 (BAI3) (AA 26-135) protein (GST tag)
BAI3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 5 % Thehalose, pH 7.2.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- BAI3 (Brain-Specific Angiogenesis Inhibitor 3 (BAI3))
- 别名
- BAI3 (BAI3 产品)
- 别名
- zgc:163001 Protein, BAI3 Protein, A830096D10Rik Protein, adhesion G protein-coupled receptor B3 Protein, brain-specific angiogenesis inhibitor 3 Protein, ADGRB3 Protein, Adgrb3 Protein, adgrb3 Protein, BAI3 Protein
- 背景
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Background: Human Brain-Specific Angiogenesis Inhibitor 3 (BAI3) is a 177 kDa seven-span transmembrane (TM) protein, which is thought to be a member of the secretin receptor family. It is synthesized by neurons of the CNS and likely is a negative regulator of angiogenesis. BAI3 is 1498 amino acids in size. It contains three distinct regions: an N-terminal extracellular domain (ECD) (aa25-883), a 7-TM segment, and a C-terminal cytoplasmic region. The ECD contains four antiangiogenic TSP type 1 repeat (aa296-508), and one GSP domain (aa 816-867) that is likely used to cleave the ECD from the membrane-bound receptor. There is one altermate splice form that shows a deletion of aa 643-665. Over aa 25-880, human BAI3 shares 98 % aa identity with mouse BAI3. BAI3 has been reported primarily in the brain, but is also localized to lung, testis, and pancreas. It might be involved in angiogenesis inhibition and suppression of glioblastoma.
Synonym: Brain-Specific Angiogenesis Inhibitor 3, BAI3, KIAA0550
- 分子量
- 97.5 kDa
- UniProt
- O60242
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