BAMBI Protein (His tag)
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- 抗原 See all BAMBI 蛋白
- BAMBI (BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This BAMBI protein is labelled with His tag.
- 原理
- Recombinant Human BAMBI Protein (His Tag)
- 序列
- Met 1-Ala 152
- 产品特性
- A DNA sequence encoding the human BAMBI extracellular domain (NP_036474.1) (Met 1-Ala 152) was expressed, fused with a C-terminal polyhistidine tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product BAMBI 蛋白
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BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI) (AA 27-152) protein (Fc Tag)
BAMBI 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI) (AA 27-152) protein (Fc Tag)BAMBI 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI) (AA 1-260) protein (GST tag)BAMBI 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI) (AA 21-152) protein (His tag)Crystallography grade BAMBI 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI) (AA 27-152) protein (His tag)Crystallography grade BAMBI 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI) (AA 21-260) protein (rho-1D4 tag)Crystallography grade BAMBI 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI) (AA 27-260) protein (rho-1D4 tag)Crystallography grade BAMBI 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- BAMBI (BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))
- 别名
- BAMBI (BAMBI 产品)
- 别名
- NMA Protein, bambi Protein, nma Protein, BAMBI Protein, Zfnma Protein, cb998 Protein, fc44c12 Protein, id:ibd5020 Protein, wu:fc44c12 Protein, wu:fe01e03 Protein, 2610003H06Rik Protein, bambi-A Protein, zgc:91871 Protein, BMP and activin membrane bound inhibitor Protein, BMP and activin membrane-bound inhibitor homolog Protein, BMP and activin membrane-bound inhibitor Protein, BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a Protein, BMP and activin membrane-bound inhibitor L homeolog Protein, BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b Protein, BAMBI Protein, bambi Protein, bambia Protein, Bambi Protein, LOC724378 Protein, LOC100647353 Protein, bambi.L Protein, bambib Protein
- 背景
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Background: BMP and activin membrane-bound inhibitor (BAMBI) is a transmembrane glycoprotein that is a pseudoreceptor of type 1 receptors. BAMBI structurally lacks intracellular serine/ threonine kinase domain but with an extracellular domain and a short cytoplasmic region that share sequence similarities with type 1 receptors, whose members have functions in signal transduction in various developing and pathological processes. BAMBI competes with the type 1 receptor, a receptor of the transforming growth factor-beta (TGF-beta), through functioning as negative regulators of TGF-beta by limiting the signaling range of the TGF-beta family during early embryogenesis. The expression of BAMBI can be induced by accumulated beta-catenin and BMP. The expression level of BAMBI was found aberrantly elevated in most colorectal and hepatocellular carcinomas relative to the corresponding non-cancerous tissues. It suggestes that beta-catenin and TGF-beta interfere growth arrest by inducing the expression of BAMBI, and this may contribute to colorectal and hepatocellular tumorigenesis.
Synonym: NMA
- 分子量
- 16.1 kDa
- NCBI登录号
- NP_036474
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