CD147 Protein (His tag,Fc Tag)
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- 抗原 See all CD147 (BSG) 蛋白
- CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This CD147 protein is labelled with His tag,Fc Tag.
- 原理
- Recombinant Mouse CD147/Basigin Protein (His & Fc Tag)(Active)
- 序列
- Met 1-Arg 209
- 产品特性
- A DNA sequence encoding the extracellular domain of mouse BSG isoform 2 (NP_001070652.1) (Met 1-Arg 209) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
- 纯度
- > 90 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Using the Octet RED System, the affinity constant (Kd) of mouse CD147-Fc bound to Human PPIA-His was 0.4 μM.
- Top Product
- Discover our top product BSG 蛋白
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Basigin (Ok Blood Group) (BSG) (AA 22-205) protein (His tag)
BSG 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Basigin (Ok Blood Group) (BSG) (AA 22-207) protein (His-DYKDDDDK-Strep II Tag)BSG 宿主: 人 宿主: HEK-293T Cells Recombinant ELISA, SDS, WB, PI
Basigin (Ok Blood Group) (BSG) (AA 22-205) protein (His tag,AVI tag,Biotin)BSG 宿主: 人 宿主: HEK-293 Cells Recombinant >92 % as determined by SDS-PAGE.
Basigin (Ok Blood Group) (BSG) protein (mFc Tag)BSG 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
Basigin (Ok Blood Group) (BSG) (AA 22-325) protein (His tag)BSG 宿主: 小鼠 宿主: 人细胞 Recombinant > 90 % as determined by SDS-PAGE
Basigin (Ok Blood Group) (BSG) protein (His tag)BSG 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by reducing SDS-PAGE.
Basigin (Ok Blood Group) (BSG) protein (His tag)BSG 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >90 % as determined by reducing SDS-PAGE.
Basigin (Ok Blood Group) (BSG) (AA 1-269) protein (GST tag)BSG 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Basigin (Ok Blood Group) (BSG) (AA 206-305) protein (GST tag)BSG 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Basigin (Ok Blood Group) (BSG) (AA 1-209) protein (His tag)BSG 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
- 别名
- CD147/Basigin (BSG 产品)
- 别名
- EMMPRIN Protein, RPE7 Protein, 5F7 Protein, CD147 Protein, M6 Protein, OK Protein, TCSF Protein, AI115436 Protein, AI325119 Protein, HT-7 Protein, 5A11 Protein, CE9 Protein, HT7 Protein, Ox47R Protein, basignin Protein, wu:fb26a05 Protein, wu:fo98e12 Protein, bsg Protein, prso03 Protein, basigin (Ok blood group) Protein, basigin Protein, basigin (Ok blood group) S homeolog Protein, BSG Protein, Bsg Protein, bsg Protein, bsg.S Protein
- 背景
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Background: CD147/EMMPRIN (Extracellular Matrix Metalloproteinase Inducer), also known as Basigin (BSG), is a transmembrane glycoprotein with different forms resulted from different modes of glycosylation and N-terminal sequence variants. It is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. Recently, CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression. Thus, CD147 and its antibody are used as an effective treatment for malignant cancers.
Synonym: Basigin, Basic immunoglobulin superfamily, HT7 antigen, Membrane glycoprotein gp42, CD147, Bsg,AI115436,AI325119,EMMPRIN,HT-7
- 分子量
- 48.6 kDa
- NCBI登录号
- NP_001070652
- 途径
- S100 Proteins
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