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ASS1 Protein (His tag)

ASS1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318178
发货至: 中国
  • 抗原 See all ASS1 蛋白
    ASS1 (Argininosuccinate Synthase 1 (ASS1))
    蛋白类型
    Recombinant
    宿主
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 4
    • 2
    • 2
    • 2
    • 2
    大肠杆菌(E. Coli)
    标记
    This ASS1 protein is labelled with His tag.
    原理
    Recombinant Human ASS1 Protein (His Tag)
    序列
    Met 1-Lys412
    产品特性
    Recombinant Human Argininosuccinate Synthase is produced by our E.coli expression system and the target gene encoding Met1-Lys412 is expressed with a 6His tag at the N-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product ASS1 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 50 mM Imidazole, 1 mM DTT, 40 % Glycerol, pH 7.5.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    ASS1 (Argininosuccinate Synthase 1 (ASS1))
    别名
    ASS1 (ASS1 产品)
    别名
    ASS Protein, CTLN1 Protein, AA408052 Protein, Ass-1 Protein, fold Protein, ASSA Protein, Ass Protein, ass Protein, zgc:92051 Protein, wu:fb95a04 Protein, wu:fc01e08 Protein, argininosuccinate synthase 1 Protein, argininosuccinate synthetase 1 Protein, argininosuccinate synthase 1 S homeolog Protein, ASS1 Protein, Ass1 Protein, ass1.S Protein, ass1 Protein
    背景

    Background: Argininosuccinate Synthase (ASS1) is an urea cycle enzyme with a tetrameric structure composed of identical subunits. ASS1 is involved in the synthesis of arginine and catalyzes that condensation of citrulline and aspartate to argininosuccinate using ATP. ASS1 is important to the urea cycle as it catalyzes the important second last step in the arginine biosynthetic pathway. ASS1 mainly expressed in periportal hepatocytes, but also in most other body tissues. A deficiency of ASS1 causes citrullinemia (CTLN1), an autosomal recessive disease which is characterized by severe vomiting spells and mental retardation.

    Synonym: Argininosuccinate Synthase, Citrulline--Aspartate Ligase, ASS1, ASS

    分子量
    42.8 kDa
    UniProt
    P00966
    途径
    Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin
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