AKR1A1 Protein (His tag)
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- 抗原 See all AKR1A1 蛋白
- AKR1A1 (Aldo-Keto Reductase Family 1, Member A1 (Aldehyde Reductase) (AKR1A1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This AKR1A1 protein is labelled with His tag.
- 原理
- Recombinant Human AKR1A1 Protein (His Tag)
- 序列
- Met 1-Tyr 325
- 产品特性
- A DNA sequence encoding the human AKR1A1 (P14550) (Met 1-Tyr 325) was expressed, with a polyhistidine tag at the N-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product AKR1A1 蛋白
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Aldo-Keto Reductase Family 1, Member A1 (Aldehyde Reductase) (AKR1A1) (AA 1-325) protein (GST tag)
AKR1A1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Aldo-Keto Reductase Family 1, Member A1 (Aldehyde Reductase) (AKR1A1) (AA 1-325) protein (His tag)AKR1A1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Aldo-Keto Reductase Family 1, Member A1 (Aldehyde Reductase) (AKR1A1) (AA 2-325) protein (His tag)Crystallography grade AKR1A1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Aldo-Keto Reductase Family 1, Member A1 (Aldehyde Reductase) (AKR1A1) (AA 2-325) protein (His tag)Crystallography grade AKR1A1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Aldo-Keto Reductase Family 1, Member A1 (Aldehyde Reductase) (AKR1A1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)AKR1A1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Aldo-Keto Reductase Family 1, Member A1 (Aldehyde Reductase) (AKR1A1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)AKR1A1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.5
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- AKR1A1 (Aldo-Keto Reductase Family 1, Member A1 (Aldehyde Reductase) (AKR1A1))
- 别名
- AKR1A1 (AKR1A1 产品)
- 别名
- akr1a1 Protein, zgc:100940 Protein, aldr1 Protein, alr Protein, arm Protein, dd3 Protein, AKR1A1 Protein, zgc:110225 Protein, ALDR1 Protein, ALR Protein, ARM Protein, DD3 Protein, Akr1a4 Protein, 2610201A18Rik Protein, ALR1 Protein, Alr Protein, aldo-keto reductase family 1, member A1a (aldehyde reductase) Protein, aldo-keto reductase family 1, member A1 (aldehyde reductase) Protein, aldo-keto reductase family 1 member A1 Protein, aldo-keto reductase family 1, member A1b (aldehyde reductase) Protein, aldehyde reductase Protein, aldo-keto reductase family 1, member A1 (aldehyde reductase) L homeolog Protein, akr1a1a Protein, akr1a1 Protein, AKR1A1 Protein, akr1a1b Protein, Akr1a1 Protein, akr1a1.L Protein
- 背景
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Background: Aldehyde reductase (AKR1A1) is a member of the aldo-keto reductase superfamily, which consists of more than 40 known enzymes and proteins that includes variety of monomeric NADPH-dependent oxidoreductases, such as aldehyde reductase. Aldehyde reductase has wide substrate specificities for carbonyl compounds. These enzymes are implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Aldehyde reductase possess a structure with a beta-alpha-beta fold which contains a novel NADP-binding motif. The binding site is located in a large, deep, elliptical pocket in the C-terminal end of the beta sheet, the substrate being bound in an extended conformation. This binding is more similar to FAD- than to NAD(P)-binding oxidoreductases. AKR1A1 is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue.
Synonym: ALDR1,ALR,ARM,DD3,HEL-S-6
- 分子量
- 39 kDa
- UniProt
- P14550
- 途径
- Monocarboxylic Acid Catabolic Process
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