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ALDH7A1 Protein (His tag)

ALDH7A1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 93 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317523
发货至: 中国
  • 抗原 See all ALDH7A1 蛋白
    ALDH7A1 (Aldehyde Dehydrogenase 7 Family, Member A1 (ALDH7A1))
    蛋白类型
    Recombinant
    宿主
    • 4
    • 3
    • 2
    资源
    • 5
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This ALDH7A1 protein is labelled with His tag.
    原理
    Recombinant Human ALDH7A1/ATQ1 Protein (His Tag)
    序列
    Ser 2-Gln 511
    产品特性
    A DNA sequence encoding the human ALDH7A1 isoform 2 (P49419-2) (Ser 2-Gln 511) was expressed, with a polyhistide tag at the N-terminus.
    纯度
    > 93 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product ALDH7A1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile 50 mM Tris, 500 mM NaCl, 20 % glycerol, pH 8.0
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    ALDH7A1 (Aldehyde Dehydrogenase 7 Family, Member A1 (ALDH7A1))
    别名
    ALDH7A1/ATQ1 (ALDH7A1 产品)
    别名
    atq1 Protein, ALDH7A1 Protein, ATQ1 Protein, EPD Protein, PDE Protein, antiquitin Protein, ATQ Protein, wu:fi34d12 Protein, wu:fi35e06 Protein, Atq1 Protein, D18Wsu181e Protein, aldehyde dehydrogenase 7 family member A1 Protein, aldehyde dehydrogenase 7 family member A1 L homeolog Protein, aldehyde dehydrogenase 7 family, member A1 Protein, aldehyde dehydrogenase family 7, member A1 Protein, ALDH7A1 Protein, aldh7a1 Protein, aldh7a1.L Protein, Aldh7a1 Protein
    背景

    Background: ALDH7A1 (Aldehyde dehydrogenase 7 family, member A1) is a member of subfamily 7 in the aldehyde dehydrogenase family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Mammalian ALDH7A1 is homologous to plant ALDH7B1 which protects against various forms of stress such as increased salinity, dehydration and treatment with oxidants or pesticides. In mammals, ALDH7A1 is known to play a primary role during lysine catabolism through the NAD+-dependent oxidative conversion of aminoadipate semialdehyde (AASA) to its corresponding carboxylic acid, α-aminoadipic acid. Deleterious mutations in human ALDH7A1 are responsible for pyridoxine-dependent and folinic acid-responsive seizures. ALDH7A1 is a novel aldehyde dehydrogenase expressed in multiple subcellular compartments that protects against hyperosmotic stress by generating osmolytes and metabolizing toxic aldehydes.

    Synonym: ATQ1;EPD;PDE

    分子量
    56 kDa
    途径
    Sensory Perception of Sound
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