ALDH4A1 Protein (GST tag,His tag)
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- 抗原 See all ALDH4A1 蛋白
- ALDH4A1 (Aldehyde Dehydrogenase 4 Family, Member A1 (ALDH4A1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This ALDH4A1 protein is labelled with GST tag,His tag.
- 原理
- Recombinant Human ALDH4A1 Protein (His & GST Tag)
- 序列
- Lys 25-Gln 563
- 产品特性
- A DNA sequence encoding the mature form of human ALDH4A1 (AAH07581.1) (Lys 25-Gln 563) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- 纯度
- > 80 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product ALDH4A1 蛋白
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Aldehyde Dehydrogenase 4 Family, Member A1 (ALDH4A1) (AA 1-563) protein (GST tag)
ALDH4A1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Aldehyde Dehydrogenase 4 Family, Member A1 (ALDH4A1) (AA 25-563) protein (His tag)Crystallography grade ALDH4A1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Aldehyde Dehydrogenase 4 Family, Member A1 (ALDH4A1) (AA 24-562) protein (His tag)Crystallography grade ALDH4A1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.5, 10 % glycerol
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- ALDH4A1 (Aldehyde Dehydrogenase 4 Family, Member A1 (ALDH4A1))
- 别名
- ALDH4A1 (ALDH4A1 产品)
- 别名
- aldh4 Protein, p5cd Protein, p5cdh Protein, ALDH4 Protein, P5CD Protein, P5CDh Protein, A930035F14Rik Protein, Ahd-1 Protein, Ahd1 Protein, Aldh4 Protein, Aldh5a1 Protein, E330022C09 Protein, P5cd Protein, P5cdh Protein, P5cdhl Protein, P5cdhs Protein, Ssdh1 Protein, zgc:63592 Protein, aldehyde dehydrogenase 4 family member A1 Protein, aldehyde dehydrogenase 4 family, member A1 Protein, aldehyde dehydrogenase 4 family member A1 L homeolog Protein, aldh4a1 Protein, ALDH4A1 Protein, Aldh4a1 Protein, aldh4a1.L Protein
- 背景
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Background: ALDH4A1 is a member of the aldehyde dehydrogenase family. Aldehyde dehydrogenase enzymes function in the metabolism of many molecules including certain fats (cholesterol and other fatty acids) and protein building blocks (amino acids). Additional aldehyde dehydrogenase enzymes detoxify external substances, such as alcohol and pollutants, and internal substances, such as toxins that are formed within cells. ALDH4A1 is expressed abundantly in liver followed by skeletal muscle, kidney, heart, brain, placenta, lung and pancreas. It is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Defects in ALDH4A1 are the cause of hyperprolinemia type 2 (HP-2). HP-2 is characterized by the accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. The disorder may be causally related to neurologic manifestations, including seizures and mental retardation.
Synonym: ALDH4,P5CD,P5CDh
- 分子量
- 86.8 kDa
- 途径
- Monocarboxylic Acid Catabolic Process
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