ALDH1A3 Protein (His tag)
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- 抗原 See all ALDH1A3 蛋白
- ALDH1A3 (Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This ALDH1A3 protein is labelled with His tag.
- 原理
- Recombinant Human ALDH1A3 Protein (His Tag)
- 序列
- Met1-Pro512
- 产品特性
- Recombinant Human ALDH1A3 is produced by our E.coli expression system and the target gene encoding Met1-Pro512 is expressed with a 6His tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mMNaCl, pH 7.5,20 % Glycerol.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- ALDH1A3 (Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3))
- 别名
- ALDH1A3 (ALDH1A3 产品)
- 别名
- RALDH3 Protein, ALDH1A3 Protein, ALDH1A6 Protein, ALDH6 Protein, MCOP8 Protein, Aldh6 Protein, V1 Protein, aldehyde dehydrogenase 1 family member A3 Protein, aldehyde dehydrogenase 1 family member A3 L homeolog Protein, aldehyde dehydrogenase 1 family, member A3 Protein, aldehyde dehydrogenase family 1, subfamily A3 Protein, ALDH1A3 Protein, aldh1a3.L Protein, aldh1a3 Protein, Aldh1a3 Protein
- 背景
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Background: Aldehyde dehydrogenase 1 family member A3 (ALDH1A3), also known as retinaldehyde dehydrogenase 3 (RALDH3), is a member of the aldehyde dehydrogenase family known to metabolize a wide variety of aldehydes. ALDH1A3 specifically oxidizes retinal to retinoic acid (RA) and is differentially expressed in developing embryonic tissues and adult organs. The RA produced by ALDH1A3 in rodents contributes to the development of skin and hair follicles, brain, tooth buds, lungs, olfactory bulbs, kidneys, eyes, skeletal muscle and seminal vesicles. In recent research, ALDH1A3 could be as a marker of cancer stem cell to predict metastasis or clinical prognosis in many cancers.
Synonym: Aldehyde dehydrogenase family 1 member A3, ALDH1A3, Aldehyde dehydrogenase 6, Retinaldehyde dehydrogenase 3, RALDH-3, ALDH6,ALDH1A6,MCOP8,RALDH3
- 分子量
- 57.5 kDa
- UniProt
- P47895
- 途径
- Retinoic Acid Receptor Signaling Pathway
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