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ASXL1 Protein (GST tag)

ASXL1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319711
发货至: 中国
  • 抗原 See all ASXL1 蛋白
    ASXL1 (Additional Sex Combs Like 1 (ASXL1))
    蛋白类型
    Recombinant
    宿主
    • 5
    • 1
    资源
    • 2
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This ASXL1 protein is labelled with GST tag.
    原理
    Recombinant Human ASXL1 Protein (GST Tag)
    序列
    Lys1477-Arg154
    产品特性
    Recombinant Human ASXL1 is produced by our E.coli expression system and the target gene encoding Lys1477-Arg1541 is expressed with a GST tag at the N-terminus.
    纯度
    > 90 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product ASXL1 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    ASXL1 (Additional Sex Combs Like 1 (ASXL1))
    别名
    ASXL1 (ASXL1 产品)
    别名
    asxl1 Protein, MGC83850 Protein, mKIAA0978 Protein, BOPS Protein, MDS Protein, additional sex combs like 1, transcriptional regulator L homeolog Protein, additional sex combs like 1, transcriptional regulator Protein, additional sex combs like 1 Protein, asxl1.L Protein, ASXL1 Protein, asxl1 Protein, Asxl1 Protein
    背景

    Background: Putative Polycomb group protein ASXL1 involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). It acts as coactivator of RARA and RXRA through association with NCOA1. ASXL1 also acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner, the function seems to involve differential recruitment of methylated histone H3 to respective promoters.

    Synonym: Putative Polycomb group protein ASXL1, Additional sex combs-like protein 1, ASXL1, KIAA0978,

    分子量
    33.6 kDa
    UniProt
    Q8IXJ9
    途径
    Retinoic Acid Receptor Signaling Pathway
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