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ADAM15 Protein (His tag)

ADAM15 宿主: 人 宿主: HEK-293 Cells Recombinant > 97 % as determined by reducing SDS-PAGE.
产品编号 ABIN7194150
发货至: 中国
  • 抗原 See all ADAM15 蛋白
    ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))
    蛋白类型
    Recombinant
    宿主
    • 7
    • 4
    • 1
    资源
    • 6
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This ADAM15 protein is labelled with His tag.
    原理
    Recombinant Human ADAM15 Protein (HEK293 Cells, His Tag)
    序列
    Met 1-Thr 696
    产品特性
    A DNA sequence encoding the human ADAM15 (NP_997074.1) (Met 1-Thr 696) precursor with a C-terminal polyhistidine tag was expressed.
    纯度
    > 97 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product ADAM15 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))
    别名
    ADAM15 (ADAM15 产品)
    别名
    ADAM15 Protein, mdc15 Protein, MDC15 Protein, metargidin Protein, tMDCVI Protein, ADAM metallopeptidase domain 15 Protein, ADAM metallopeptidase domain 15 L homeolog Protein, a disintegrin and metallopeptidase domain 15 (metargidin) Protein, ADAM15 Protein, adam15.L Protein, adam15 Protein, Adam15 Protein
    背景

    Background: ADAM15, also known as Metargidin, is a type I transmembrane glycoprotein belonging to the ADAM (A Disintegrin and Metalloprotease Domain) family of proteins and is widely expressed in different tissues and cell types. Members of this family contain an amino-terminal metalloprotease domain followed by a disintegrin domain, a cysteine-rich region and a membrane proximal EGF-like domain. The disintegrin domain of ADAM15/metargidin contains an RGD tripeptide sequence, suggesting that it may potentially interact with the integrin family of proteins. ADAM15 is a transmembrane multi-domain proteins implicated in proteolysis, cell-cell and cell-matrix interactions in various disease conditions. There is also evidence supporting a role for ADAM15 in angiogenesis and angioinvasion of tumor cells, which are critical for unrestrained tumor growth and metastatic spread. Given its diverse functions, ADAM15 may represent a pivotal regulatory component of tumor progression, an important target for therapeutic intervention, or emerge as a biomarker of disease progression.

    Synonym: MDC15

    分子量
    54 kDa
    NCBI登录号
    NP_997074
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