ACOX1 Protein (His tag)
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- 抗原 See all ACOX1 蛋白
- ACOX1 (Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This ACOX1 protein is labelled with His tag.
- 原理
- Recombinant Human ACOX1/aox Protein (His Tag)
- 序列
- Met 1-Leu 660
- 产品特性
- A DNA sequence encoding the human ACOX1 (AAH08767.1) (Met 1-Leu 660) was expressed, with a polyhistidine tag at the N-terminus.
- 纯度
- > 85 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product ACOX1 蛋白
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Acyl-CoA Oxidase 1, Palmitoyl (ACOX1) (AA 306-395) protein (His-IF2DI Tag)
ACOX1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Acyl-CoA Oxidase 1, Palmitoyl (ACOX1) (AA 1-660) protein (GST tag)ACOX1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.0, 20 % glycerol, 3 mM DTT
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- ACOX1 (Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))
- 别名
- ACOX1/aox (ACOX1 产品)
- 别名
- zgc:92584 Protein, wu:fb59h12 Protein, zgc:114033 Protein, aco Protein, acox Protein, ACOX Protein, PALMCOX Protein, SCOX Protein, RATACOA1 Protein, AOX Protein, Acox Protein, D130055E20Rik Protein, Paox Protein, PCOX1 Protein, acyl-CoA oxidase 1 Protein, acyl-CoA oxidase 1, palmitoyl Protein, acyl-CoA oxidase 1, palmitoyl L homeolog Protein, acyl-Coenzyme A oxidase 1, palmitoyl Protein, ACOX1 Protein, acox1 Protein, acox1.L Protein, Acox1 Protein
- 背景
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Background: Peroxisomal acyl-coenzyme A oxidase 1(ACOX1 or AOX) is the first enzyme of the fatty acid beta-oxidation pathway and belongs to the Acyl-CoA oxidase family. Human liver peroxisomes contain two acyl-CoA oxidases, namely, palmitoyl-CoA oxidase (ACOX1/AOX) and a branched chain acyl-CoA oxidase. The palmitoyl-CoA oxidase (ACOX1/AOX) oxidizes the CoA esters of straight chain fatty acids and prostaglandins and donates electrons directly to molecular oxygen, thereby producing H2O2. Human ACOX1/AOX is a protein of 661-amino acids, including the carboxyl-terminal sequence(Ser-Lys-Leu) known as a minimal peroxisome-targeting signal. Human ACOX1/AOX, the first and rate-limiting enzyme of the peroxisomal β-oxidation pathway, has two isoforms including ACOX1a and ACOX1b, transcribed from a single gene. The human ACOX1b isoform is more effective than the ACOX1a isoform in reversing the Acox1 null phenotype in the mouse partly because of the Substrate utilization differences.
Synonym: ACOX;PALMCOX;SCOX
- 分子量
- 76.7 kDa
- 途径
- Regulation of Lipid Metabolism by PPARalpha, Monocarboxylic Acid Catabolic Process
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