SARS-CoV-2 Spike S2 Protein (BA.1 - Omicron) (His tag)
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- 抗原 See all SARS-CoV-2 Spike S2 蛋白
- SARS-CoV-2 Spike S2
- 蛋白类型
- Recombinant
- 产品特性
- BA.1 - Omicron
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宿主
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron
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资源
- HEK-293 Cells
- 标记
- This SARS-CoV-2 Spike S2 protein is labelled with His tag.
- 原理
- SARS-CoV-2 Spike S2 protein, His Tag (BA.1/Omicron)
- 序列
- Ser 683 - Pro 1210
- 产品特性
- SARS-CoV-2 S2 protein, His Tag (BA.1/Omicron) is expressed from human 293 cells (HEK293). It contains AA Ser 686 - Pro 1213 (Accession # QHD43416.1 (N764K, D796Y, N856K, Q954H, N969K, L981F, F817P, A892P, A899P, A942P, K986P, V987P). The mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.1; GISAID clade: GRA; Nextstrain clade: 21K). Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) are introduced to prevent the formation of aggregates in the course of protein production.
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product SARS-CoV-2 Spike S2 蛋白
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SARS-CoV-2 Spike S2 (B.1.351 - beta) (Active) protein (His tag)
宿主: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
SARS-CoV-2 Spike S2 protein (His tag)宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. SDS
SARS-CoV-2 Spike S2 (B.1.1.7 - alpha) (Active) protein (His tag)宿主: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Alpha 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
SARS-CoV-2 Spike S2 (P.1 - gamma) (Active) protein (His tag)宿主: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Gamma 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
SARS-CoV-2 Spike S2 (Active) protein (His tag)宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
SARS-CoV-2 Spike S2 (Active) protein (His tag,AVI tag,Biotin)宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- 应用备注
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 59.9 kDa. The protein migrates as 70-80 kDa under reducing (R) condition due to glycosylation.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
- 储存方法
- -20°C
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- 抗原
- SARS-CoV-2 Spike S2
- 别名
- SARS-CoV-2 Spike S2 protein (SARS-CoV-2 Spike S2 产品)
- 别名
- E2 Protein, Surface Glycoprotein Protein, S Protein
- 背景
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Synonyms: Spike,S2 protein,Spike glycoprotein Subunit2,S glycoprotein Subunit2,Spike protein S2,
It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. - 分子量
- 59.9 kDa
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