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KIR3DL3 Protein (Fc Tag)

KIR3DL3 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
产品编号 ABIN7121540
发货至: 中国
  • 抗原 See all KIR3DL3 products
    KIR3DL3 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 3 (KIR3DL3))
    蛋白类型
    Recombinant
    宿主
    资源
    • 3
    • 2
    • 1
    HEK-293 Cells
    标记
    This KIR3DL3 protein is labelled with Fc Tag.
    原理
    Human KIR3DL3 / CD158z Protein, Fc Tag
    序列
    Gln 26 - Leu 322
    产品特性
    Human KIR3DL3, Fc Tag (KI3-H5259) is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Leu 322 (Accession # Q8N743-1).
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
  • 应用备注
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 58.7 kDa. The protein migrates as 66 kDa under reducing (R) condition due to glycosylation.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    51 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
    储存条件
    -20 °C
    储存方法
    -20°C
  • 抗原
    KIR3DL3 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 3 (KIR3DL3))
    别名
    KIR3DL3 / CD158z (KIR3DL3 产品)
    别名
    CD158Z Protein, KIR3DL7 Protein, KIR44 Protein, KIRC1 Protein, killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3 Protein, KIR3DL3 Protein
    背景
    Synonyms: Killer cell immunoglobulin-like receptor 3DL3,CD158 antigen-like family member Z,Killer cell inhibitory receptor 1,CD158z,KIR3DL3,KIR3DL7,KIRC1,
    Description: the inhibitory KIR surface receptors possessing three extracellular immunoglobin (Ig) domains (3D) and only one inhibitory motif within the long cytoplasmic domain (L) due to a premature stop codon. Moreover, exon 6 of KIR3DL3 encoding the stem part of the receptor is also absent, which differs from other inhibitory KIRs. Understanding the function of KIR3DL3 is further complicated by the unknown identity of the specific ligand, but its importance is highlighted by its presence in all human KIR haplotypes with 120 distinct polymorphic alleles of the coding sequence [
    分子量
    58.7 kDa
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