This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 78.3 kDa. The protein migrates as 66-70 kDa under reducing (R) condition due to glycosylation.
限制
仅限研究用
状态
Liquid
缓冲液
PBS, 1 mM EDTA, 0.5 mM TCEP, pH 7.4
储存条件
-80 °C
储存方法
-70°C
抗原
PADI2
(Peptidyl Arginine Deiminase, Type II (PADI2))
PADI2 Protein, PAD-H19 Protein, PAD2 Protein, PDI2 Protein, Pdi Protein, Pdi2 Protein, mKIAA0994 Protein, peptidyl arginine deiminase 2 Protein, peptidyl arginine deiminase, type II Protein, protein-arginine deiminase type-2 Protein, peptidyl arginine deiminase, type II S homeolog Protein, PADI2 Protein, padi2 Protein, LOC100357368 Protein, padi2.S Protein, Padi2 Protein
背景
Synonyms: PADI2,PAD-H19,KIAA0994,PAD2,PDI2, Description: Protein-arginine deiminase type-2 (PADI2) are calcium-dependent histone-modifying enzymes whose activity is dysregulated in inflammatory diseases and cancer. This enzyme which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages.