SOSTDC1 Protein (Fc Tag)
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- 抗原 See all SOSTDC1 蛋白
- SOSTDC1 (Sclerostin Domain Containing 1 (SOSTDC1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This SOSTDC1 protein is labelled with Fc Tag.
- 原理
- Human USAG-1 Protein, Fc Tag
- 序列
- Phe 24 - Ser 206
- 产品特性
- Human USAG-1, Fc Tag (US1-H5254) is expressed from human 293 cells (HEK293). It contains AA Phe 24 - Ser 206 (Accession # Q6X4U4-1).
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product SOSTDC1 蛋白
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- 应用备注
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 47.2 kDa. The protein migrates as 45-65 kDa under reducing (R) condition due to glycosylation.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- 51 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
- 储存条件
- -20 °C
- 储存方法
- -20°C
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- 抗原
- SOSTDC1 (Sclerostin Domain Containing 1 (SOSTDC1))
- 别名
- USAG-1 (SOSTDC1 产品)
- 别名
- SOSTDC1 Protein, zgc:110293 Protein, DKFZp469J0531 Protein, Usag1 Protein, ECTODIN Protein, USAG1 Protein, 0610006G05Rik Protein, Sostl Protein, USAG-1 Protein, Wise Protein, ectodin Protein, WISE Protein, sclerostin domain containing 1 Protein, sclerostin domain containing 1a Protein, SOSTDC1 Protein, sostdc1a Protein, Sostdc1 Protein
- 背景
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Synonyms: Uterine sensitization-associated gene 1 protein,
Description: USAG1 (uterine sensitization associated gene 1), also known asSOSTDC1 (sclerostin domain-containing 1), Ectodin, is a secreted protein with a glycosylated N-terminus that contains a C-terminal cysteine knot domain. This C-terminal cysteine knot domain is present in numerous growth factors, including TGFβ, NGF, PDGF, vWF, NDP, and mucin-2, and involved in dimerization, receptor binding, and signal transduction. SOSTDC1 negatively regulates BMP signaling during cellular proliferation, differentiation, and apoptosis in several biological processes (such as dentary morphogenesis, embryo implantation in the endo-metrium, and healing of bone fractures) [8]. In addition, SOSTDC1 might also involve cancer development processes through the regulation of the Wnt pathway. - 分子量
- 47.2 kDa
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