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CLEC5A Protein (His tag)

MALS verified CLEC5A 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
产品编号 ABIN7121255
发货至: 中国
  • 抗原 See all CLEC5A 蛋白
    CLEC5A (C-Type Lectin Domain Family 5, Member A (CLEC5A))
    蛋白类型
    Recombinant
    宿主
    • 4
    • 3
    • 1
    • 1
    资源
    • 3
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This CLEC5A protein is labelled with His tag.
    原理
    Human CLEC5A / MDL-1 Protein, His Tag (MALS & SPR verified)
    序列
    Pro 28 - Lys 188
    产品特性
    Human CLEC5A, His Tag (CLA-H5243) is expressed from human 293 cells (HEK293). It contains AA Pro 28 - Lys 188 (Accession # Q9NY25-1).
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    质量等级
    MALS verified
    Top Product
    Discover our top product CLEC5A 蛋白
  • 应用备注
    This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 20.3 kDa. The protein migrates as 60-66 kDa under reducing (R) condition due to glycosylation.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    储存条件
    -20 °C
    储存方法
    -20°C
  • 抗原
    CLEC5A (C-Type Lectin Domain Family 5, Member A (CLEC5A))
    别名
    CLEC5A / MDL-1 (CLEC5A 产品)
    别名
    CLECSF5 Protein, MDL-1 Protein, MDL1 Protein, Clecsf5 Protein, Ly100 Protein, Mdl1 Protein, C-type lectin domain containing 5A Protein, C-type lectin domain family 5, member a Protein, CLEC5A Protein, Clec5a Protein
    背景
    Synonyms: CLEC5A,CLECSF5,superfamilymember 5,C-type lectin domain family 5, member A,MDL1,MDL-1,DAP12-associating lectin 1,
    Description: CLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily.CLEC5A is expressed on monocytes, macrophages, and neutrophils. Its expression is up-regulated on monocytes in rheumatoid arthritis. CLEC5A with dnax-activation protein 12 and may play a role in cell activation. It also functions as a positive regulator of osteoclastogenesis. CLEC5A acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation .The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.
    分子量
    20.3 kDa
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