LAMa4 Protein (His tag)
LAMa4
宿主: 人
宿主: HEK-293 Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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- 抗原 See all LAMa4 蛋白
- LAMa4 (Laminin, alpha 4 (LAMa4))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This LAMa4 protein is labelled with His tag.
- 原理
- Recombinant human LAMA4 protein with C-terminal 6xHis tag
- 特异性
- LAMA4 (Ala25-Ala1823) 6xHis tag
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- affinity purification
- 纯度
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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- Discover our top product LAMa4 蛋白
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Laminin, alpha 4 (LAMa4) (AA 1-120) protein (GST tag)
LAMa4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with deionized water
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- LAMa4 (Laminin, alpha 4 (LAMa4))
- 别名
- LAMA4 (LAMa4 产品)
- 别名
- si:dkey-119m7.3 Protein, si:busm1-189a20.2 Protein, CMD1JJ Protein, LAMA3 Protein, LAMA4*-1 Protein, RGD1560062 Protein, laminin subunit alpha 4 Protein, laminin, alpha 4 Protein, LAMA4 Protein, lama4 Protein, Lama4 Protein
- 背景
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Synonymes: Laminin-14 subunit alpha, Laminin-8 subunit alpha, Laminin-9 subunit alpha
Description: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the alpha chain isoform laminin, alpha 4. The domain structure of alpha 4 is similar to that of alpha 3, both of which resemble truncated versions of alpha 1 and alpha 2, in that approximately 1,200 residues at the N-terminus (domains IV, V and VI) have been lost. Laminin, alpha 4 contains the C-terminal G domain which distinguishes all alpha chains from the beta and gamma chains. The RNA analysis from adult and fetal tissues revealed developmental regulation of expression, however, the exact function of laminin, alpha 4 is not known. Tissue-specific utilization of alternative polyA-signal has been described in literature. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2011] - 分子量
- predicted molecular mass of 200.7 kDa after removal of the signal peptide.
- UniProt
- Q16363
- 途径
- Brown Fat Cell Differentiation
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