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IL-11 Protein (AA 22-199) (His tag)

IL11 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
产品编号 ABIN7013692
发货至: 中国
  • 抗原 See all IL-11 (IL11) 蛋白
    IL-11 (IL11) (Interleukin 11 (IL11))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 22-199
    宿主
    • 17
    • 11
    • 2
    • 2
    资源
    • 13
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This IL-11 protein is labelled with His tag.
    原理
    Human IL-11 Protein, His Tag
    纯度
    >90 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IL11 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    储存条件
    -20 °C
  • 抗原
    IL-11 (IL11) (Interleukin 11 (IL11))
    别名
    IL-11 (IL11 产品)
    别名
    IL11 Protein, AGIF Protein, IL-11 Protein, Il-11 Protein, interleukin 11 Protein, IL11 Protein, Il11 Protein
    背景
    Interleukin-11 (IL-11) is a pleiotropic cytokine that stimulates megakaryocytopoiesis, resulting in increased production of platelets, as well as activating osteoclasts, inhibiting epithelial cell proliferation and apoptosis, and inhibiting macrophage mediator production. These functions may be particularly important in mediating the hematopoietic, osseous and mucosal protective effects of IL-11. The cytokine also possesses anti-inflammatory activity, and has been proposed as a therapeutic agent in the treatment of chronic inflammatory diseases, such as Crohn's disease and rheumatoid arthritis. Although IL-11 was initially believed to be restricted to mammals, subsequent studies demonstrated it to be expressed in fish. Despite close similarity in gene structure and conservation of key amino acids between fish and mammalian IL-11, they share relatively low overall amino acid identity and may not necessarily be functionally analogous.
    分子量
    21.0 kDa
    NCBI登录号
    NP_000632
    途径
    JAK/STAT Signaling, Negative Regulation of Hormone Secretion
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