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CD34 Protein (CD34) (AA 32-290) (His tag)

CD34 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
产品编号 ABIN7013676
发货至: 中国
  • 抗原 See all CD34 蛋白
    CD34
    蛋白类型
    Recombinant
    产品特性
    AA 32-290
    宿主
    • 15
    • 8
    • 1
    • 1
    资源
    • 9
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This CD34 protein is labelled with His tag.
    产品特性
    Human CD34 Protein, His Tag
    纯度
    >90 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product CD34 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    储存条件
    -20 °C
  • 抗原
    CD34
    别名
    CD34 (CD34 产品)
    别名
    AU040960 Protein, CD34 molecule Protein, CD34 antigen Protein, CD34 Protein, Cd34 Protein
    背景
    CD34 Molecule is a cluster of differentiation molecule present on certain cells within the human body. It is a cell surface glycoprotein and functions as a cell-cell adhesion factor. It may also mediate the attachment of stem cells to bone marrow extracellular matrix or directly to stromal cells. As a ~ 110 kDa monomeric cell surface antigen, CD34 is highly glycosylated with nine potential N-linked and numerous potential O-linked glycosylation sites in its extracellular domain. The CD34 protein is a member of a family of single-pass transmembrane sialomucin proteins that show expression on early hematopoietic and vascular-associated tissue. CD34 is also an important adhesion molecule and is required for T cells to enter lymph nodes. It is expressed on lymph node endothelia whereas the L-selectin to which it binds is on the T cell. It was indicated that CD34 is a phosphorylation target for activated PKC, and couples to the hematopoietic adapter protein CrkL, which were involved in CD34 signaling pathways. CD34 is abberantly expressed in many kinds of tumors and is implicated in leukemogenesis.
    分子量
    29.4 kDa
    NCBI登录号
    NP_001020280
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