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CD8 Protein (CD8) (AA 22-182) (His tag)

CD8 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN7013442
发货至: 中国
  • 抗原 See all CD8 蛋白
    CD8
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 22-182
    宿主
    资源
    • 1
    • 1
    HEK-293 Cells
    标记
    This CD8 protein is labelled with His tag.
    产品特性
    Human CD8 alpha&beta (CD8A&CD8B) Heterodimer Protein, His Tag&Tag Free (MALS verified)
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
  • 应用备注
    MALS verified
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    储存条件
    -20 °C
  • 抗原
    CD8
    别名
    CD8 alpha & beta (CD8 产品)
    别名
    CD8 Protein, Leu2 Protein, MAL Protein, p32 Protein, CD8a molecule Protein, CD8A Protein
    背景
    Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. CD8A forms disulfide-linked heterodimers with CD8B at the cell surface. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells. Additionally, CD8B plays a critical role in thymic selection of CD8+ T-cells. A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched.
    分子量
    19.5 kDa (CD8A) & 22.1 kDa (CD8B)
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