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CTGF Protein (AA 27-349) (His tag,AVI tag,Biotin)

CTGF 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
产品编号 ABIN7013364
发货至: 中国
  • 抗原 See all CTGF 蛋白
    CTGF (Connective Tissue Growth Factor (CTGF))
    蛋白类型
    Recombinant
    产品特性
    AA 27-349
    宿主
    • 20
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    资源
    • 25
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This CTGF protein is labelled with His tag,AVI tag,Biotin.
    序列
    AA 27-349
    特异性
    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
    纯度
    >90 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product CTGF 蛋白
  • 说明

    Ready-to-use AvitagTM biotinylated protein:
    The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Tris with Potassium glutamate and Arginine,  pH 7.0
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
  • 抗原
    CTGF (Connective Tissue Growth Factor (CTGF))
    别名
    CTGF (CTGF 产品)
    别名
    Ccn2 Protein, Fisp12 Protein, Hcs24 Protein, fisp-12 Protein, CCN2 Protein, HCS24 Protein, IGFBP8 Protein, NOV2 Protein, CTGRP Protein, ctgf Protein, hm:zeh1559 Protein, si:dkey-266k12.4 Protein, wu:fl25c03 Protein, zeh1559 Protein, zgc:136644 Protein, XCTGF Protein, ccn2 Protein, nov2 Protein, hcs24 Protein, igfbp8 Protein, CTGF Protein, si:ch211-173b8.2 Protein, connective tissue growth factor Protein, connective tissue growth factor a Protein, connective tissue growth factor L homeolog Protein, connective tissue growth factor b Protein, Ctgf Protein, CTGF Protein, ctgfa Protein, ctgf.L Protein, ctgf Protein, ctgfb Protein
    背景
    Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CCN1-6) family of modular matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Analysis of CCN2 function in vivo has focused primarily on its key role as a mediator of excess ECM synthesis in multiple fibrotic diseases.
    分子量
    39.2 kDa
    NCBI登录号
    NP_001892
    途径
    Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Growth Factor Binding
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